Immune responses to human fungal pathogens and therapeutic prospects
MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …
[HTML][HTML] Candidalysin: discovery and function in Candida albicans infections
Highlights•Candidalysin is the first peptide toxin identified in any human fungal pathogen.•
Candidalysin is critical for Candida albicans mucosal and systemic infections.•Candidalysin …
Candidalysin is critical for Candida albicans mucosal and systemic infections.•Candidalysin …
Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors
MIA Hassan, K Voigt - Medical Mycology, 2019 - academic.oup.com
Fungi of the basal lineage order Mucorales are able to cause infections in animals and
humans. Mucormycosis is a well-known, life-threatening disease especially in patients with …
humans. Mucormycosis is a well-known, life-threatening disease especially in patients with …
Mucormycosis in 2023: An update on pathogenesis and management
Mucormycosis (MCR) is an emerging and frequently lethal fungal infection caused by the
Mucorales family, with Rhizopus, Mucor, and Lichtheimia, accounting for> 90% of all cases …
Mucorales family, with Rhizopus, Mucor, and Lichtheimia, accounting for> 90% of all cases …
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
J Ho, X Yang, SA Nikou, N Kichik, A Donkin… - Nature …, 2019 - nature.com
Candida albicans is a fungal pathobiont, able to cause epithelial cell damage and immune
activation. These functions have been attributed to its secreted toxin, candidalysin, though …
activation. These functions have been attributed to its secreted toxin, candidalysin, though …
GRP78 and integrins play different roles in host cell invasion during mucormycosis
Mucormycosis, caused by Rhizopus species, is a life-threatening fungal infection that occurs
in patients immunocompromised by diabetic ketoacidosis (DKA), cytotoxic chemotherapy …
in patients immunocompromised by diabetic ketoacidosis (DKA), cytotoxic chemotherapy …
Connecting the dots: interplay of pathogenic mechanisms between COVID-19 disease and mucormycosis
Coronavirus disease (COVID-19)-associated mucormycosis (CAM) is an emerging threat
globally, especially in India. More than 40,000 CAM cases have been reported in India. The …
globally, especially in India. More than 40,000 CAM cases have been reported in India. The …
[HTML][HTML] Mucormycosis and COVID-19 pandemic: Clinical and diagnostic approach
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
yet to be controlled worldwide, especially in India. The second wave of coronavirus disease …
yet to be controlled worldwide, especially in India. The second wave of coronavirus disease …
Pathogenic strategies of Pseudogymnoascus destructans during torpor and arousal of hibernating bats
M Isidoro-Ayza, BS Klein - Science, 2024 - science.org
Millions of hibernating bats across North America have died from white-nose syndrome
(WNS), an emerging disease caused by a psychrophilic (cold-loving) fungus …
(WNS), an emerging disease caused by a psychrophilic (cold-loving) fungus …
Mucorales species and macrophages
Mucormycosis is an emerging fungal infection caused by Mucorales with an unacceptable
high mortality rate. Mucorales is a complex fungal group, including eleven different genera …
high mortality rate. Mucorales is a complex fungal group, including eleven different genera …