Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Tuberculosis (TB) and HIV co-infections place an immense burden on health care systems
and pose particular diagnostic and therapeutic challenges. Infection with HIV is the most …

Background In sub-Saharan Africa, the burden of human immunodeficiency virus (HIV)–
associated tuberculosis is high. We conducted a trial with a 2-by-2 factorial design to assess …

Combination antiretroviral therapy for HIV infection improves immune function and
eliminates the risk of AIDS-related complications but does not restore full health. HIV …

A low CD4/CD8 ratio in elderly HIV-uninfected adults is associated with increased morbidity
and mortality. A subset of HIV-infected adults receiving effective antiretroviral therapy (ART) …

Background. Defining the association of non–AIDS-defining events with inflammation and
immune activation among human immunodeficiency virus (HIV)–infected persons with …

Background. While inflammation predicts mortality in treated human immunodeficiency virus
(HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell …

HIV-1 proviruses persist in the CD4+ T cells of HIV-infected individuals despite years of
combination antiretroviral therapy (cART) with suppression of HIV-1 RNA levels< 40 …

Despite complete or near‐complete suppression of human immunodeficiency virus (HIV)
replication with combination antiretroviral therapy, both HIV and chronic …

Background. Serious non-AIDS events cause substantial disease and death despite human
immunodeficiency virus (HIV) suppression with antiretroviral therapy (ART). Biomarkers of …