Intraventricular haemorrhage (IVH) continues to be a major complication of prematurity that
can result in cerebral palsy and cognitive impairment in survivors. No optimal therapy exists …

Oligodendrocytes (OLGs) are generated late in development and myelination is thus a
tardive event in the brain developmental process. It is however maintained whole life long at …

Intraventricular hemorrhage (IVH) is a cause of significant morbidity and mortality and is an
independent predictor of a worse outcome in intracerebral hemorrhage (ICH) and germinal …

Background and Purpose—Severe intraventricular hemorrhage (IVH) in premature infants
and the ensuing posthemorrhagic hydrocephalus cause significant mortality and …

Neural stem/precursor cells in the adult brain reside in the subventricular zone (SVZ) of the
lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus in the hippocampus …

Oligodendrocyte progenitor cells (OPCs) differentiate to myelin-producing mature
oligodendrocytes and enwrap growing or demyelinated axons during development and post …

During brain development, the immune system mediates neurogenesis, gliogenesis and
synapse formation. However, it remains unclear whether peripheral lymphocytes contribute …

Inhibition of histone deacetylases (HDACs) has been shown to reduce inflammation and
white matter damage after various forms of brain injury via modulation of …

Intraventricular hemorrhage (IVH) results in periventricular inflammation, hypomyelination of
the white matter, and hydrocephalus in premature infants. No effective therapy exists to …

Signaling by the many ligands of the TGFβ family strongly converges towards only five
receptor-activated, intracellular Smad proteins, which fall into two classes ie Smad2/3 and …