A genetic basis for interindividual variation in susceptibility to human infectious diseases has
been indicated by twin, adoptee, pedigree, and candidate gene studies. This has led to the …

The transcription and processing of pre-mRNA in eukaryotic cells are regulated in part by
reversible phosphorylation of the C-terminal domain of the largest RNA polymerase (RNAP) …

Historically, the laboratory mouse (Mus musculus) has been the experimental model of
choice to study pathophysiology of infection with bacterial pathogens, including natural and …

Background Host genetic factors are important determinants in tuberculosis (TB). The
SLC11A1 (or NRAMP1) gene has been studied extensively for genetic association with TB …

To facilitate the identification of tumor suppressor genes in the chromosome 3p21. 3-p22
AP20 subregion, we constructed a 3.5-Mb physical and gene map of this segment (between …

NRAMP1 (SLC11A1) is a professional phagocyte membrane importer of divalent metals that
contributes to iron recycling at homeostasis and to nutritional immunity against infection …

[目的] 探讨Nramp1 基因第6 内含子多态在大白猪和松辽黑猪(是由杜洛克, 长白猪和民猪合成)
中的分布及其与猪免疫抗病的关系.[方法] 采用PCR-RFLP 法对165 头大白猪和109 …

Many enzymes make “mistakes”. Consequently, repair enzymes have evolved to correct
these mistakes. For example, lactate dehydrogenase (LDH) and mitochondrial malate …

Although genetic variants in SLC11A1 (NRAMP1) have been associated with mycobacterial
diseases, these findings have not been extensively validated in pulmonary Mycobacterium …

The PCR-restriction fragment length polymorphism (RFLP) in and around TM4 of SLC11A1
gene and its association with the incidences of brucellosis in Hariana breed (Bos indicus) …