HPIDB 2.0: a curated database for host–pathogen interactions

MG Ammari, CR Gresham, FM McCarthy, B Nanduri - Database, 2016 - academic.oup.com
Identification and analysis of host–pathogen interactions (HPI) is essential to study infectious
diseases. However, HPI data are sparse in existing molecular interaction databases …

[HTML][HTML] Host-pathogen protein-nucleic acid interactions: A comprehensive review

A Jain, S Mittal, LP Tripathi, R Nussinov… - Computational and …, 2022 - Elsevier
Recognition of pathogen-derived nucleic acids by host cells is an effective host strategy to
detect pathogenic invasion and trigger immune responses. In the context of pathogen …

DeepViral: prediction of novel virus–host interactions from protein sequences and infectious disease phenotypes

W Liu-Wei, Ş Kafkas, J Chen, NJ Dimonaco… - …, 2021 - academic.oup.com
Motivation Infectious diseases caused by novel viruses have become a major public health
concern. Rapid identification of virus–host interactions can reveal mechanistic insights into …

Analysis of protein targets in pathogen–host interaction in infectious diseases: a case study on Plasmodium falciparum and Homo sapiens interaction network

S Saha, K Sengupta, P Chatterjee… - Briefings in …, 2018 - academic.oup.com
Infection and disease progression is the outcome of protein interactions between pathogen
and host. Pathogen, the role player of Infection, is becoming a severe threat to life as …

Host-microbiome protein-protein interactions capture disease-relevant pathways

H Zhou, JF Beltrán, IL Brito - Genome Biology, 2022 - Springer
Background Host-microbe interactions are crucial for normal physiological and immune
system development and are implicated in a variety of diseases, including inflammatory …

[HTML][HTML] In silico drug design for Staphylococcus aureus and development of host-pathogen interaction network

RM Wadapurkar, MD Shilpa, AKS Katti… - Informatics in Medicine …, 2018 - Elsevier
Staphylococcus aureus, a member of Staphylococcacea has been considered as an
opportunistic pathogen in humans and livestock. Thus, the suggestion has been made to …

Systematic evaluation of machine learning methods for identifying human–pathogen protein–protein interactions

H Chen, F Li, L Wang, Y Jin, CH Chi… - Briefings in …, 2021 - academic.oup.com
In recent years, high-throughput experimental techniques have significantly enhanced the
accuracy and coverage of protein–protein interaction identification, including human …

Machine-learning-based predictor of human–bacteria protein–protein interactions by incorporating comprehensive host-network properties

X Lian, S Yang, H Li, C Fu, Z Zhang - Journal of proteome …, 2019 - ACS Publications
The large-scale identification of protein–protein interactions (PPIs) between humans and
bacteria remains a crucial step in systematically understanding the underlying molecular …

Genome composition and phylogeny of microbes predict their co-occurrence in the environment

OK Kamneva - PLoS computational biology, 2017 - journals.plos.org
The genomic information of microbes is a major determinant of their phenotypic properties,
yet it is largely unknown to what extent ecological associations between different species …

HMI-PRED: a web server for structural prediction of host-microbe interactions based on interface mimicry

E Guven-Maiorov, A Hakouz, S Valjevac… - Journal of molecular …, 2020 - Elsevier
Microbes, commensals, and pathogens, control the numerous functions in the host cells.
They can alter host signaling and modulate immune surveillance by interacting with the host …