Cellular and molecular biology of cancer stem cells in melanoma: Possible therapeutic implications

M Marzagalli, M Raimondi, F Fontana… - Seminars in Cancer …, 2019 - Elsevier
Malignant melanoma is a tumor characterized by a very high level of heterogeneity,
responsible for its malignant behavior and ability to escape from standard therapies. In this …

Updating the research on the chemopreventive and therapeutic role of the peptide lunasin

CC Hsieh, C Martínez‐Villaluenga… - Journal of the …, 2018 - Wiley Online Library
Chronic diseases have become the medical challenge of the 21st century because of their
high incidence and mortality rates. Modulation of diet and lifestyle habits is considered as …

A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye

A Sarkar, N Gogia, N Glenn, A Singh, G Jones… - Scientific Reports, 2018 - nature.com
Abstract Alzheimer's disease (AD), a fatal progressive neurodegenerative disorder, also
results from accumulation of amyloid-beta 42 (Aβ42) plaques. These Aβ42 plaques trigger …

MicroRNA-92 Expression in CD133+ Melanoma Stem Cells Regulates Immunosuppression in the Tumor Microenvironment via Integrin-Dependent Activation of …

C Shidal, NP Singh, P Nagarkatti, M Nagarkatti - Cancer research, 2019 - AACR
In addition to being refractory to treatment, melanoma cancer stem cells (CSC) are known to
suppress host antitumor immunity, the underlying mechanisms of which need further …

Lunasin as a promising plant-derived peptide for cancer therapy

SM Alves de Souza, B Hernández-Ledesma… - International Journal of …, 2022 - mdpi.com
Cancer has become one of the main public health problems worldwide, demanding the
development of new therapeutic agents that can help reduce mortality. Lunasin is a soybean …

Current state of art after twenty years of the discovery of bioactive peptide lunasin

S Fernández-Tomé, B Hernández-Ledesma - Food research international, 2019 - Elsevier
Non-communicable diseases have become the medical challenge of the 21st century
because of their high incidence and mortality rates. Accumulating evidence has suggested …

The Radical Scavenging Activities and Anti-Wrinkle Effects of Soymilk Fractions Fermented with Lacticaseibacillus paracasei MK1 and Their Derived Peptides

S Lee, SP Choi, H Jeong, WK Yu, SW Kim, YS Park - Antioxidants, 2023 - mdpi.com
Soybean-derived peptides exert several beneficial effects in various experimental models.
However, only a few studies have focused on the radical scavenging and anti-wrinkle effects …

Effect of melanoma stem cells on melanoma metastasis

Q Yin, X Shi, S Lan, H Jin, D Wu - Oncology Letters, 2021 - spandidos-publications.com
Cancer stem cells (CSCs) are involved in the metastatic process, the resistance of many
types of cancer to therapeutic treatments and consequently the onset of recurrences. The …

[PDF][PDF] Bioactive peptides from le-gumes as anticancer therapeutic agents

M González-Montoya, E Cano-Sampedro… - Int J Cancer Clin …, 2017 - researchgate.net
Food proteins are a source of nutraceutical and bioactive peptides that promote health and
prevent diseases. Legume seed proteins have been widely studied to produce peptides …

Inhibitory effects of peptide lunasin in colorectal cancer HCT-116 cells and their tumorsphere-derived subpopulation

S Fernández-Tomé, F Xu, Y Han… - International Journal of …, 2020 - mdpi.com
The involvement of cancer stem-like cells (CSC) in the tumor pathogenesis has profound
implications for cancer therapy and chemoprevention. Lunasin is a bioactive peptide from …