[HTML][HTML] Adapting liposomes for oral drug delivery
Liposomes mimic natural cell membranes and have long been investigated as drug carriers
due to excellent entrapment capacity, biocompatibility and safety. Despite the success of …
due to excellent entrapment capacity, biocompatibility and safety. Despite the success of …
Bile acid transporter-mediated oral drug delivery
Bile acids are synthesized in the liver, stored in the gallbladder, and secreted into the
duodenum at meals. Apical sodium-dependent bile acid transporter (ASBT), an ileal Na+ …
duodenum at meals. Apical sodium-dependent bile acid transporter (ASBT), an ileal Na+ …
Bile acids transporters of enterohepatic circulation for targeted drug delivery
R Durník, L Šindlerová, P Babica, O Jurček - Molecules, 2022 - mdpi.com
Bile acids (BAs) are important steroidal molecules with a rapidly growing span of
applications across a variety of fields such as supramolecular chemistry, pharmacy, and …
applications across a variety of fields such as supramolecular chemistry, pharmacy, and …
On the role of bile salts in the digestion of emulsified lipids
The objective of this study was to understand quantitatively the role that bile salts play in the
digestion of emulsified lipids. The behaviours of digestion by pancreatin (1.6 mg/mL) of …
digestion of emulsified lipids. The behaviours of digestion by pancreatin (1.6 mg/mL) of …
Liposomes loaded with phenolic extracts of Spirulina LEB-18: Physicochemical characterization and behavior under simulated gastrointestinal conditions
AR Machado, AC Pinheiro, AA Vicente… - Food research …, 2019 - Elsevier
Liposomes composed of rice (RL) and soybean (SL) lecithins were produced by reverse
phase evaporation and used for the encapsulation of phenolic extracts from Spirulina LEB …
phase evaporation and used for the encapsulation of phenolic extracts from Spirulina LEB …
The Paradox of Coenzyme Q10 in Aging
ME Díaz-Casado, JL Quiles, E Barriocanal-Casado… - Nutrients, 2019 - mdpi.com
Coenzyme Q (CoQ) is an essential endogenously synthesized molecule that links different
metabolic pathways to mitochondrial energy production thanks to its location in the …
metabolic pathways to mitochondrial energy production thanks to its location in the …
Food-grade nanoparticles for encapsulation, protection and delivery of curcumin: Comparison of lipid, protein, and phospholipid nanoparticles under simulated …
The potential of three nanoparticle-based delivery systems to improve curcumin
bioavailability was investigated: lipid nPs (nanoemulsions); protein nPs (zein …
bioavailability was investigated: lipid nPs (nanoemulsions); protein nPs (zein …
Morphology of bile salts micelles and mixed micelles with lipolysis products, from scattering techniques and atomistic simulations
Hypotheses Bile salts (BS) are biosurfactants released into the small intestine, which play
key and contrasting roles in lipid digestion: they adsorb at interfaces and promote the …
key and contrasting roles in lipid digestion: they adsorb at interfaces and promote the …
Impact of gut microbiota-mediated bile acid metabolism on the solubilization capacity of bile salt micelles and drug solubility
In recent years, the gut microbiome has gained increasing appreciation as a determinant of
the health status of the human host. Bile salts that are secreted into the intestine may be …
the health status of the human host. Bile salts that are secreted into the intestine may be …
Preparation, characterization and in vitro evaluation of eudragit S100-coated bile salt-containing liposomes for Oral colonic delivery of budesonide
H Alghurabi, T Tagami, K Ogawa, T Ozeki - Polymers, 2022 - mdpi.com
The aim of this study was to prepare a liposomal formulation of a model drug (budesonide)
for colonic delivery by incorporating a bile salt (sodium glycocholate, SGC) into liposomes …
for colonic delivery by incorporating a bile salt (sodium glycocholate, SGC) into liposomes …