Probiotics, prebiotics, and phytogenic substances for optimizing gut health in poultry

AA Shehata, S Yalçın, JD Latorre, S Basiouni, YA Attia… - Microorganisms, 2022 - mdpi.com
The gut microbiota has been designated as a hidden metabolic 'organ'because of its
enormous impact on host metabolism, physiology, nutrition, and immune function. The …

Cannabinoid receptors and the endocannabinoid system: signaling and function in the central nervous system

S Zou, U Kumar - International journal of molecular sciences, 2018 - mdpi.com
The biological effects of cannabinoids, the major constituents of the ancient medicinal plant
Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Endocannabinoid signaling at the periphery: 50 years after THC

M Maccarrone, I Bab, T Bíró, GA Cabral, SK Dey… - Trends in …, 2015 - cell.com
In 1964, the psychoactive ingredient of Cannabis sativa, Δ 9-tetrahydrocannabinol (THC),
was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed …

Endocannabinoids—at the crossroads between the gut microbiota and host metabolism

PD Cani, H Plovier, M Van Hul, L Geurts… - Nature Reviews …, 2016 - nature.com
Various metabolic disorders are associated with changes in inflammatory tone. Among the
latest advances in the metabolism field, the discovery that gut microorganisms have a major …

Comprehensive review of medicinal marijuana, cannabinoids, and therapeutic implications in medicine and headache: what a long strange trip it's been…

EP Baron - Headache: The Journal of Head and Face Pain, 2015 - Wiley Online Library
Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

Modulating the endocannabinoid system in human health and disease–successes and failures

P Pacher, G Kunos - The FEBS journal, 2013 - Wiley Online Library
The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …

Overview of cannabidiol (CBD) and its analogues: Structures, biological activities, and neuroprotective mechanisms in epilepsy and Alzheimer's disease

H Li, Y Liu, D Tian, L Tian, X Ju, L Qi, Y Wang… - European journal of …, 2020 - Elsevier
Herein, 11 general types of natural cannabinoids from Cannabis sativa as well as 50 (-)-
CBD analogues with therapeutic potential were described. The underlying molecular …

Pharmacological properties, therapeutic potential, and legal status of Cannabis sativa L.: An overview

P Kumar, DK Mahato, M Kamle, R Borah… - Phytotherapy …, 2021 - Wiley Online Library
Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational
and medicinal purposes. In many countries, cannabis‐based medicines have been …

Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …