[HTML][HTML] Neural network surrogate and projected gradient descent for fast and reliable finite element model calibration: A case study on an intervertebral disc

M Atad, G Gruber, M Ribeiro, LF Nicolini, R Graf… - Computers in Biology …, 2025 - Elsevier
Accurate calibration of finite element (FE) models is essential across various biomechanical
applications, including human intervertebral discs (IVDs), to ensure their reliability and use …

Torque-and muscle-driven flexion induce disparate risks of in vitro herniation: A multiscale and multiphasic structure-based finite element study

M Zhou, RD Huff, Y Abubakr… - Journal of …, 2022 - asmedigitalcollection.asme.org
The intervertebral disc is a complex structure that experiences multiaxial stresses regularly.
Disc failure through herniation is a common cause of lower back pain, which causes …

Comparative FEM study on intervertebral disc modeling: Holzapfel-Gasser-Ogden vs. structural rebars

G Gruber, LF Nicolini, M Ribeiro, T Lerchl… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction: Numerical modeling of the intervertebral disc (IVD) is challenging due to its
complex and heterogeneous structure, requiring careful selection of constitutive models and …

Neck mobility in the Jurassic plesiosaur Cryptoclidus eurymerus: finite element analysis as a new approach to understanding the cervical skeleton in fossil vertebrates

T Wintrich, R Jonas, HJ Wilke, L Schmitz, PM Sander - PeerJ, 2019 - peerj.com
The sauropterygian clade Plesiosauria arose in the Late Triassic and survived to the very
end of the Cretaceous. Plesiosauria evolved the greatest species diversity of any marine …

Validation and Estimation of Obesity-Induced Intervertebral Disc Degeneration through Subject-Specific Finite Element Modelling of Functional Spinal Units

NK Singh, NK Singh, R Verma, AD Diwan - Bioengineering, 2024 - mdpi.com
(1) Background: Intervertebral disc degeneration has been linked to obesity; its potential
mechanical effects on the intervertebral disc remain unknown. This study aimed to develop …

An experimental-numerical method for the calibration of finite element models of the lumbar spine

LF Nicolini, A Beckmann, M Laubach… - Medical Engineering & …, 2022 - Elsevier
We present a systematic and automated stepwise method to calibrate computational models
of the spine. For that purpose, a sequential resection study on one lumbar specimen (L2-L5) …

Don't You (Project Around Discs)? Neural Network Surrogate and Projected Gradient Descent for Calibrating an Intervertebral Disc Finite Element Model

M Atad, G Gruber, M Ribeiro, LF Nicolini, R Graf… - arXiv preprint arXiv …, 2024 - arxiv.org
Accurate calibration of finite element (FE) models of human intervertebral discs (IVDs) is
essential for their reliability and application in diagnosing and planning treatments for spinal …

[HTML][HTML] Towards a validated patient-specific computational modeling framework to identify failure regions in traditional growing rods in patients with early onset …

A Agarwal, M Kodigudla, A Kelkar, D Jayaswal… - North American Spine …, 2021 - Elsevier
Background While growing rods are an important contribution to early-onset scoliosis
treatment, rod fractures are a common complication that require reoperations. A recent …

Patient-specific spine digital twins: a computational characterization of the idiopathic scoliosis

D Landinez, CF Rodríguez… - Journal of Orthopaedic …, 2025 - Springer
Background: Scoliosis is an idiopathic three-dimensional spine strain. The orthopedic
parameter used to diagnose and evaluate the severity of the strain is Cobb's angle. This …

Influence of structural and material property uncertainties on biomechanics of intervertebral discs-Implications for disc tissue engineering

W Wang, C Zhou, R Guo, T Cha, G Li - Journal of the Mechanical Behavior …, 2021 - Elsevier
This study investigated how variations of structural and material properties of human
intervertebral discs (IVDs) affect the biomechanical responses of the IVDs under simulated …