Micron-scale magnetic resonance imaging based on low temperatures and dynamic nuclear polarization

R Tycko - Progress in Nuclear Magnetic Resonance …, 2023 - Elsevier
Extension of magnetic resonance imaging (MRI) techniques to the single micron scale has
been the goal of research in multiple laboratories over several decades. It has proven …

Enhanced spatial resolution in magnetic resonance imaging by dynamic nuclear polarization at 5 K

HY Chen, CB Wilson, R Tycko - Proceedings of the …, 2022 - National Acad Sciences
Spatial resolution in MRI is ultimately limited by the signal detection sensitivity of NMR, since
resolution equal to ρiso in all three dimensions requires the detection of NMR signals from a …

Solid-state MAS NMR at ultra low temperature of hydrated alanine doped with DNP radicals

Y Li, R Chaklashiya, H Takahashi, Y Kawahara… - Journal of Magnetic …, 2021 - Elsevier
Magic angle spinning (MAS) nuclear magnetic resonance (NMR) experiments at ultra low
temperature (ULT)(≪ 100 K) have demonstrated clear benefits for obtaining large signal …

Nitroxide-based triradical dopants for efficient low-temperature dynamic nuclear polarization in aqueous solutions over a broad pH range

WM Yau, CB Wilson, J Jeon, R Tycko - Journal of Magnetic Resonance, 2022 - Elsevier
Dynamic nuclear polarization (DNP) can provide substantial sensitivity enhancements in
solid state nuclear magnetic resonance (ssNMR) measurements on frozen solutions …

[HTML][HTML] Advanced high resolution three-dimensional imaging to visualize the cerebral neurovascular network in stroke

C Zeng, Z Chen, H Yang, Y Fan, L Fei… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
As an important method to accurately and timely diagnose stroke and study physiological
characteristics and pathological mechanism in it, imaging technology has gone through …

Slice selection in low-temperature, DNP-enhanced magnetic resonance imaging by Lee-Goldburg spin-locking and phase modulation

HY Chen, R Tycko - Journal of Magnetic Resonance, 2020 - Elsevier
Large enhancements in nuclear magnetic resonance (NMR) signals provided by dynamic
nuclear polarization (DNP) at low temperatures have the potential to enable inductively …

Sensitivity analysis of magic angle spinning dynamic nuclear polarization below 6 K

PT Judge, EL Sesti, EP Saliba, N Alaniva… - Journal of Magnetic …, 2019 - Elsevier
Dynamic nuclear polarization (DNP) improves signal-to-noise in nuclear magnetic
resonance (NMR) spectroscopy. Signal-to-noise in NMR can be further improved with …

[引用][C] Low temperature, DNP-enhanced magnetic resonance microimaging

HY Chen, R Tycko