Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

STAT6: a review of a signaling pathway implicated in various diseases with a special emphasis in its usefulness in pathology

G Karpathiou, A Papoudou-Bai, E Ferrand… - … -Research and Practice, 2021 - Elsevier
Abstract Signal Transducer and Activator of Transcription 6 (STAT6), belonging to a family of
seven similar members is primarily stimulated by interleukin (IL)-4 and IL-13, and acts as a T …

Non–IgE-or mixed IgE/non–IgE-mediated gastrointestinal food allergies in the first years of life: Old and new tools for diagnosis

M Calvani, C Anania, B Cuomo, E D'Auria, F Decimo… - Nutrients, 2021 - mdpi.com
non-IgE and mixed gastrointestinal food allergies present various specific, well-
characterized clinical pictures such as food protein-induced allergic proctocolitis, food …

Short-chain fatty acids augment differentiation and function of human induced regulatory T cells

M Hu, B Alashkar Alhamwe, B Santner-Nanan… - International Journal of …, 2022 - mdpi.com
Regulatory T cells (Tregs) control immune system activity and inhibit inflammation. While, in
mice, short-chain fatty acids (SCFAs) are known to be essential regulators of naturally …

Epigenomic and epigenetic investigations of food allergy

Y Chun, JH Lee, S Bunyavanich - Pediatric Allergy and …, 2024 - Wiley Online Library
As a potential link between genetic predisposition, environmental exposures, and food
allergy outcomes, epigenetics has been a molecular variable of interest in ongoing efforts to …

Non-covalent binding of whey protein isolate after ultrasound pretreatment to epigallocatechin gallate: Effects on immune response and gut microbiota in BALB/c mice

Y Meng, H Zhu, L Han, Z Xu, Y Zou, K Ma… - International Journal of …, 2023 - Elsevier
Cow's milk is one of the “big eight” most common allergenic foods, and β-lactoglobulin and α-
Lactalbumin in whey protein are two major allergens of cow's milk protein. An effective …

Epigenetics in food allergy and immunomodulation

JA Cañas, R Núñez, A Cruz-Amaya, F Gómez… - Nutrients, 2021 - mdpi.com
Food allergy (FA) is an increasing problem worldwide and, over recent years, its prevalence
is rising in developed countries. Nowadays, the immunological and cellular processes that …

Raw milk kefir: microbiota, bioactive peptides, and immune modulation

T Baars, B van Esch, L van Ooijen, Z Zhang… - Food & Function, 2023 - pubs.rsc.org
This study aims to characterize the microbiota and peptidomic composition of raw milk kefir,
and to address the potential anti-allergic effects of raw milk kefir using validated research …

The pathogenesis of food allergy and protection offered by dietary compounds from the perspective of epigenetics

F Yang, X Zhang, Y Xie, J Yuan, J Gao, H Chen… - The Journal of Nutritional …, 2024 - Elsevier
Food allergy is a global food safety concern, with an increasing prevalence in recent
decades. However, the immunological and cellular mechanisms involved in allergic …

MALAT1 induces food allergy by promoting release of IL-6 from dendritic cells and suppressing the immunomodulatory function of Tregs

H Feng, X Xiong, Z Chen, N Luo… - Journal of asthma and …, 2022 - Taylor & Francis
Background Dendritic cells (DCs) comprise a valuable target for immune-modulation in food
allergy (FA). Long noncoding RNA (lncRNA), metastasis associated lung adenocarcinoma …