In the last decades three-dimensional (3D) in vitro cancer models have been proposed as a
bridge between bidimensional (2D) cell cultures and in vivo animal models, the gold …

Simple Summary Invasive lobular breast cancer (ILC) is the second most common
histological subtype of invasive breast cancer, which is noted to have a unique microscopic …

Breast cancer is now globally the most frequent cancer and leading cause of women's
death. Two thirds of breast cancers express the luminal estrogen receptor-positive (ERα+) …

Introduction The clinical prognosis of the HER2-overexpressing (HER2-OE) subtype of
breast cancer (BC) is influenced by the immune infiltrate of the tumor. Specifically, monocytic …

Background Breast cancer is the most prevalent cancer in women globally. Over-activated
estrogen receptor (ER) α signaling is considered the main factor in luminal breast cancers …

Simple Summary Breast cancer is a major health concern as it remains the deadliest for
women worldwide. As for other cancer types, the immune system is determinant for how the …

During the past 15 years, a plethora of innovative 3D in vitro systems has been developed.
They offer the possibility of identifying crucial cellular and molecular contributors to the …

Breast cancer risk continues to increase post menopause. Anti-estrogen therapies are
available to prevent postmenopausal breast cancer in high-risk women. However, their …

Abstract Advanced three-dimensional (3D) cell models have proven to be capable of
depicting architectural and microenvironmental features of several tissues. By providing data …

Breast cancer is a complex, highly heterogenous, and dynamic disease and the leading
cause of cancer‐related death in women worldwide. Evaluation of the heterogeneity of …