Machine learning models for classification and identification of significant attributes to detect type 2 diabetes

KC Howlader, MS Satu, MA Awal, MR Islam… - … information science and …, 2022 - Springer
Abstract Type 2 Diabetes (T2D) is a chronic disease characterized by abnormally high blood
glucose levels due to insulin resistance and reduced pancreatic insulin production. The …

Recent applications of bioinformatics in target identification and drug discovery for Alzheimer's disease

SK Singh, A Kumar, RB Singh, P Ghosh… - Current topics in …, 2022 - benthamdirect.com
Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disease
characterized by progressive memory loss. The main pathological features of the disease …

Identification of biomarkers and pathways for the SARS-CoV-2 infections that make complexities in pulmonary arterial hypertension patients

TA Taz, K Ahmed, BK Paul, FA Al-Zahrani… - Briefings in …, 2021 - academic.oup.com
This study aimed to identify significant gene expression profiles of the human lung epithelial
cells caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …

Exploring gene regulatory interaction networks and predicting therapeutic molecules for hypopharyngeal cancer and EGFR‐mutated lung adenocarcinoma

A Bhattacharjya, MM Islam, MA Uddin… - FEBS Open …, 2024 - Wiley Online Library
Hypopharyngeal cancer gene regulatory networks and therapeutic molecules are a disease
that is associated with EGFR‐mutated lung adenocarcinoma. Here we utilized a …

[HTML][HTML] Detection of molecular signatures and pathways shared in inflammatory bowel disease and colorectal cancer: a bioinformatics and systems biology approach

M Al-Mustanjid, SMH Mahmud, MRI Royel… - Genomics, 2020 - Elsevier
Emerging evidence indicates IBD is a risk factor for the increasing incidence of colorectal
cancer (CRC) development. We used a system biology approach to identify common …

Identification of novel noninvasive diagnostics biomarkers in the Parkinson's diseases and improving the disease classification using support vector machine

S Moradi, L Tapak, S Afshar - BioMed Research International, 2022 - Wiley Online Library
Background. Parkinson's disease (PD) is a neurological disorder that is marked by the deficit
of neurons in the midbrain that changes motor and cognitive function. In the substantia nigra …

[HTML][HTML] Proteomics and its application in the research of acupuncture: An updated review

Z Zhong, MM Sun, M He, HP Huang, GY Hu, SQ Ma… - Heliyon, 2024 - Elsevier
As a complementary and alternative therapy, acupuncture is widely used in the prevention
and treatment of various diseases. However, the understanding of the mechanism of …

[HTML][HTML] Detection of molecular signatures and pathways shared by Alzheimer's disease and type 2 diabetes

J Shu, N Li, W Wei, L Zhang - Gene, 2022 - Elsevier
Alzheimer's disease (AD) and type 2 diabetes (T2D) are common in the general elderly
population, conferring heavy individual, social, and economic stresses on families and …

Revealing genetic links of Type 2 diabetes that lead to the development of Alzheimer's disease

M Afzal, KS Alharbi, SI Alzarea, NM Alyamani, I Kazmi… - Heliyon, 2023 - cell.com
Background A factor leading to Alzheimer's Disease (AD), portrayed by peripheral insulin
resistance, is Type 2 diabetes mellitus (T2D). The likelihood of T2D cases would be at …

Identification of Comorbidities, Genomic Associations, and Molecular Mechanisms for COVID‐19 Using Bioinformatics Approaches

SBS Omit, S Akhter, HK Rana… - BioMed Research …, 2023 - Wiley Online Library
Several studies have been done to identify comorbidities of COVID‐19. In this work, we
developed an analytical bioinformatics framework to reveal COVID‐19 comorbidities, their …