Important flavonoids and their role as a therapeutic agent
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …
Bioavailability of hesperidin and its aglycone hesperetin—compounds found in citrus fruits as a parameter conditioning the pro-health potential (neuroprotective and …
K Wdowiak, J Walkowiak, R Pietrzak, A Bazan-Woźniak… - Nutrients, 2022 - mdpi.com
Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits.
They possess a variety of pharmacological properties such as neuroprotective and …
They possess a variety of pharmacological properties such as neuroprotective and …
Effects of polyphenols on insulin resistance
G Williamson, K Sheedy - Nutrients, 2020 - mdpi.com
Insulin resistance (IR) is apparent when tissues responsible for clearing glucose from the
blood, such as adipose and muscle, do not respond properly to appropriate signals. IR is …
blood, such as adipose and muscle, do not respond properly to appropriate signals. IR is …
The effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose–response meta-analysis
Hesperidin is a naturally occurring bioactive compound that may have an impact on
cardiovascular disease risks, but the evidence is not conclusive. To investigate further, this …
cardiovascular disease risks, but the evidence is not conclusive. To investigate further, this …
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration
J Zhu, R Sun, C Yan, K Sun, L Gao, B Zheng, J Shi - Cell Cycle, 2023 - Taylor & Francis
Intervertebral disc degeneration (IVDD), a widely known contributor to low back pain (LBP),
has been proved to be a global health challenging conundrum. Hesperidin (hesperetin-7-O …
has been proved to be a global health challenging conundrum. Hesperidin (hesperetin-7-O …
[HTML][HTML] Hesperidin ameliorates benign prostatic hyperplasia by attenuating cell proliferation, inflammatory response, and epithelial-mesenchymal transition via the …
HJ Kim, BR Jin, HJ An - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Excessively activated transforming growth factor-beta 1 (TGF-β1) exacerbates benign
prostatic hyperplasia (BPH) by triggering epithelial-mesenchymal transition (EMT) as well as …
prostatic hyperplasia (BPH) by triggering epithelial-mesenchymal transition (EMT) as well as …
Effects of orange juice intake on cardiovascular risk factors: A systematic review and meta‐analysis of randomized controlled clinical trials
M Motallaei, N Ramezani‐Jolfaie… - Phytotherapy …, 2021 - Wiley Online Library
Previous investigations exploring the effects of orange juice (OJ) as a nutrient‐dense
beverage on cardiovascular risk factors were inconsistent. We aimed to conduct a …
beverage on cardiovascular risk factors were inconsistent. We aimed to conduct a …
[HTML][HTML] Promising influences of hesperidin and hesperetin against diabetes and its complications: a systematic review of molecular, cellular, and metabolic effects
A Mirzaei, A Mirzaei, SN Khalilabad, VR Askari… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Hesperidin and hesperetin, two flavonoids with potential therapeutic value, have been
extensively studied in the context of diabetes management. The main objective of this …
extensively studied in the context of diabetes management. The main objective of this …
Quality assessment method for Chinpi, dried Citrus spp. peel and its derived Kampo medicines using specific monoclonal antibody against hesperidin
K Noguchi, D Imahori, Y Kido… - Phytochemical …, 2023 - Wiley Online Library
Abstract Introduction Hesperidin (hesperetin 7‐rutinoside, HP), a flavonoid glycoside found
in Citrus unshiu Marcowicz or Citrus reticulata Blanco (Rutaceae), has been reported to …
in Citrus unshiu Marcowicz or Citrus reticulata Blanco (Rutaceae), has been reported to …
The effect of perioperative vitamin C on postoperative analgesic consumption: A meta-analysis of randomized controlled trials
KC Hung, YT Lin, KH Chen, LK Wang, JY Chen… - Nutrients, 2020 - mdpi.com
Because the analgesic effect of vitamin C against acute pain remains poorly addressed, this
meta-analysis aimed at investigating its effectiveness against acute postoperative pain. A …
meta-analysis aimed at investigating its effectiveness against acute postoperative pain. A …