The homoeostatic regulation of metabolism is highly complex and involves multiple inputs
from both the nervous and endocrine systems. The gut is the largest endocrine organ in our …

The amyloid hypothesis, the assumption that beta-amyloid toxicity is the primary cause of
neuronal and synaptic loss, has been the mainstream research concept in Alzheimer's …

The incidence of nonalcoholic fatty liver disease (NAFLD) keeps rising year by year, and
NAFLD is rapidly becoming the most common liver disease worldwide. Clinical studies have …

Endoplasmic reticulum (ER) stress generally occurs in secretory cell types. It has been
reported that Leydig cells, which produce testosterone in response to human chorionic …

Alzheimer's disease (AD) is the most prevalent dementia in the world. Its cause (s) are
presently largely unknown. The most common explanation for AD, now, is the amyloid …

The metabolic benefits of intermittent fasting (IF) have been well recognized. However,
limited studies have examined the relationship between long‐term maternal IF before …

Branched-chain amino acids (BCAA) found in protein are most notably known for their ability
to increase protein synthesis, explaining their appeal to athletes seeking muscle …

Arrhythmogenic cardiomyopathy (ACM), a fatal heart disease characterized by
fibroadipocytic replacement of cardiac myocytes, accounts for 20% of sudden cardiac death …

Background The mechanism by which Roux-en-Y Gastric Bypass (RYGB) increases the
secretion of glucagon-like peptide-1 (GLP-1) remains incompletely defined. Here we …

Metformin is an effective oral hypoglycaemic agent used in the treatment of type 2 diabetes
mellitus; however, its use in pregnancy for the treatment of gestational diabetes mellitus …