Immunopathogenicity of Acanthamoeba spp. in the Brain and Lungs

K Kot, N Łanocha-Arendarczyk… - International Journal of …, 2021 - mdpi.com
Free-living amoebas, including Acanthamoeba spp., are widely distributed in soil, water, and
air. They are capable of causing granulomatous amebic encephalitis, Acanthamoeba …

CRISPR/Cas9-mediated knockout of Lcn2 in human breast cancer cell line MDA-MB-231 ameliorates erastin-mediated ferroptosis and increases cisplatin vulnerability

MR Valashedi, AM Roushandeh, K Tomita… - Life sciences, 2022 - Elsevier
Abstract Aims Lipocalin 2 (Lcn2) is an antioxidant-related protein upregulated in various
cellular stress conditions, especially cancer. In this study, we abrogated Lcn2 expression in …

Encystation and Stress Responses under the Control of Ubiquitin-like Proteins in Pathogenic Amoebae

A Samba-Louaka, E Labruyère, M Matondo… - Microorganisms, 2023 - mdpi.com
Amoebae found in aquatic and terrestrial environments encompass various pathogenic
species, including the parasite Entamoeba histolytica and the free-living Acanthamoeba …

Inhibitory effects and mechanism of antifungal action of the natural cyclic depsipeptide, aureobasidin A against Cryptococcus neoformans

M Teymuri, M Shams-Ghahfarokhi… - Bioorganic & Medicinal …, 2021 - Elsevier
Cryptococcosis is an opportunistic fungal infection caused mainly by Cryptococcus
neoformans. The aim of the present study was to evaluate the inhibitory effect of …

The role of Acanthamoeba castellanii (T4 genotype) antioxidant enzymes in parasite survival under H2O2-induced oxidative stress

S Motavallihaghi, I Khodadadi, F Goudarzi… - Parasitology …, 2022 - Elsevier
Acanthamoeba castellanii (A. castellanii) is an important opportunistic parasite. Induction of
oxidative stress by the host immune system is one of the most important defense strategies …

[HTML][HTML] Toxoplasma gondii: A possible inducer of oxidative stress in reproductive system of male rats

ZHA Nazarlu, M Matini, M Bahmanzadeh… - Iranian journal of …, 2020 - ncbi.nlm.nih.gov
Background: Toxoplasmosis is suspected to have adverse effects on the male reproductive
system. We aimed to determine the possible role of Toxoplasma gondii in oxidative stress in …

Investigating the effect of parasites (toxoplasma gondii RH strain, Leishmania major (MRHO/IR/75/ER), and hydatid cyst) antigens on Alzheimer's disease: An in vivo …

N Barati, A Shojaeian, M Ramezani, F Kalhori… - Experimental …, 2024 - Elsevier
This study aimed to investigate the effects of parasite antigens on Alzheimer's symptoms in
animal model. Alzheimer's model was induced in Wistar rats using Amyloid-beta peptide …

High oxygen concentrations inhibit Acanthamoeba spp.

I Sifaoui, EC -Yanes, M Reyes-Batlle… - Parasitology …, 2021 - Springer
Abstract Efficacious treatments against Acanthamoeba Keratitis (AK) is challenging, often
ineffective and linked to the intragenotype variation in the drug efficacy. Increased oxygen …

Therapeutic efficacy of Kumquat-loaded chitosan nanoparticles against Toxoplasmosis in mice model

A El-Hamed, N Samy, A Abd-Rabou… - Egyptian Journal of …, 2022 - journals.ekb.eg
The goal of this study was to compare the effects of kumquat extract and its chitosan
nanoparticles on biochemical, histopathological, and parasitological factors in mice infected …

Comparative evaluation of silver nanoparticles and human platelet rich-plasma versus traditional therapy in the treatment of murine chronic toxoplasmosis

SM Ibrahim, AMF Al-Ghandour, SMA Mohamed… - Journal of Parasitic …, 2024 - Springer
Toxoplasmosis is a worldwide parasitic disease infecting about one-third of the human
population. At present, licensed medications are incapable of curing human chronic …