New and old biomarkers for diagnosis and management of chronic hepatitis B virus infection

CS Coffin, K Zhou, NA Terrault - Gastroenterology, 2019 - Elsevier
Tests to detect the presence and activity of hepatitis B virus (HBV) are the cornerstones of
diagnosis and management. Assays that detect or measure serum levels of HB surface …

Targets and future direct-acting antiviral approaches to achieve hepatitis B virus cure

T Asselah, D Loureiro, N Boyer… - … Lancet Gastroenterology & …, 2019 - thelancet.com
Around 257 million people worldwide have chronic hepatitis B virus (HBV) infection, which
leads to almost 1 million deaths per year from complications, mainly decompensated …

EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection

P Lampertico, K Agarwal, T Berg, M Buti… - Journal of …, 2017 - Elsevier
Hepatitis B virus (HBV) infection remains a global public health problem with changing
epidemiology due to several factors including vaccination policies and migration. This …

Serum hepatitis B core-related antigen (HBcrAg) correlates with covalently closed circular DNA transcriptional activity in chronic hepatitis B patients

B Testoni, F Lebossé, C Scholtes, F Berby… - Journal of …, 2019 - Elsevier
Background & Aims It has been proposed that serum hepatitis B core-related antigen
(HBcrAg) reflects intrahepatic covalently closed circular (ccc) DNA levels. However, the …

[HTML][HTML] Hepatitis B core-related antigen (HBcrAg) levels in the natural history of hepatitis B virus infection in a large European cohort predominantly infected with …

B Maasoumy, SB Wiegand, J Jaroszewicz… - Clinical Microbiology …, 2015 - Elsevier
Hepatitis B core-related antigen (HBcrAg) has been suggested as an additional marker of
hepatitis B virus (HBV) infection. HBcrAg combines the antigenic reactivity resulting from …

Clinical outcomes and predictors for relapse after cessation of oral antiviral treatment in chronic hepatitis B patients

KS Jung, JY Park, YE Chon, HS Kim, W Kang… - Journal of …, 2016 - Springer
Background Little is known about stopping rules of nucelos (t) ide analog (NA) treatment for
chronic hepatitis B (CHB). Methods A total of 113 consecutive patients with CHB (45 HBeAg …

[HTML][HTML] Viral hepatitis: Innovations and expectations

S Leoni, A Casabianca, B Biagioni… - World journal of …, 2022 - ncbi.nlm.nih.gov
Viral hepatitis is a significant health problem worldwide, associated with morbidity and
mortality. Hepatitis B, C, D, and occasionally E viruses (HBV, HCV, HDV, and HEV) can …

[HTML][HTML] KASL clinical practice guidelines for management of chronic hepatitis B

Korean Association for the Study of the … - Clinical and …, 2022 - ncbi.nlm.nih.gov
Chronic hepatitis B (CHB) is a major cause of chronic liver diseases in Korea and remains a
threat to public health due to its high morbidity and disease-related mortality. Since the latest …

Current laboratory tests for diagnosis of hepatitis B virus infection

JH Lee, HS Kim - International Journal of Clinical Practice, 2021 - Wiley Online Library
Abstract Background Hepatitis B virus (HBV) has a long history in human infectious
diseases. HBV infection can progress chronically, leading to cancer. After introduction of a …

Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC

W Shi, K Li, Y Zhang - Frontiers in Oncology, 2023 - frontiersin.org
Chronic hepatitis B virus (HBV) infection is a worldwide public health threat that results in
huge morbidity and mortality. Late diagnosis and delayed treatment of HBV infections can …