Pathogenic variants in genes encoding ion channels are causal for various pediatric and
adult neurological conditions. In particular, several epilepsy syndromes have been identified …

Dravet syndrome is a severe epileptic syndrome that begins during the first year of life of
otherwise healthy babies. Over the years, the seizure burden changes, and pathology …

Epilepsy, a neurological disease characterized by recurrent seizures, is a result of increased
excitatory signaling in the brain. While there are antiseizure medications available, a third of …