Physicochemical Features and Peculiarities of Interaction of AMP with the Membrane

M Pirtskhalava, B Vishnepolsky, M Grigolava… - Pharmaceuticals, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are anti-infectives that have the potential to be used as a
novel and untapped class of biotherapeutics. Modes of action of antimicrobial peptides …

Natural antifungal peptides/proteins as model for novel food preservatives

T Thery, KM Lynch, EK Arendt - … in food science and food safety, 2019 - Wiley Online Library
A large range of ingredients for food and food products are subject to fungal contamination,
which is a major cause of destruction of crops, exposure of animals and humans to invasive …

Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development

A Parthasarathy, EJ Borrego, MA Savka… - Journal of Biological …, 2021 - ASBMB
For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …

Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: biological activity and structural modification

M Wang, H Li, W Liu, H Cao, X Hu, X Gao, F Xu… - European Journal of …, 2020 - Elsevier
Based on the definite therapeutic benefits, such as neuroprotective, cardioprotective,
anticancer, anti-diabetic and so on, the Panax genus which contains many valuable plants …

Ultrafast Biomimetic Oxidative Folding of Cysteine‐rich Peptides and Microproteins in Organic Solvents

A Kam, S Loo, Y Qiu, CF Liu… - Angewandte Chemie …, 2024 - Wiley Online Library
Disulfides in peptides and proteins are essential for maintaining a properly folded structure.
Their oxidative folding is invariably performed in an aqueous‐buffered solution. However …

Plant peptides–redefining an area of ribosomally synthesized and post-translationally modified peptides

JR Chekan, LS Mydy, MA Pasquale… - Natural Product …, 2024 - pubs.rsc.org
Covering 1965 to February 2024Plants are prolific peptide chemists and are known to make
thousands of different peptidic molecules. These peptides vary dramatically in their size …

Anti-fungal Hevein-like peptides biosynthesized from quinoa cleavable hololectins

S Loo, SV Tay, A Kam, F Tang, JS Fan, D Yang… - Molecules, 2021 - mdpi.com
Chitin-binding hevein-like peptides (CB-HLPs) belong to a family of cysteine-rich peptides
that play important roles in plant stress and defense mechanisms. CB-HLPs are ribosomally …

Peptides as potential biomarkers for authentication of mountain-cultivated ginseng and cultivated ginseng of different ages using UPLC-HRMS

N Zhao, M Cheng, W Lv, Y Wu, D Liu… - Journal of agricultural …, 2020 - ACS Publications
The growth conditions and age of Panax ginseng are vital for determining the quality of the
ginseng plant. However, the considerable difference in price according to the cultivation …

Ginsentide TP1 protects hypoxia-induced dysfunction and ER stress-linked apoptosis

B Dutta, S Loo, A Kam, SK Sze, JP Tam - Cells, 2023 - mdpi.com
Hypoxia-induced vascular endothelial dysfunction (VED) is a significant contributor to
several severe human diseases, including heart disease, stroke, dementia, and cancer …

Hololectin interdomain linker determines asparaginyl endopeptidase-mediated maturation of antifungal hevein-like peptides in oats

S Loo, SV Tay, A Kam, W Lee, JP Tam - Frontiers in plant science, 2022 - frontiersin.org
Heveins and hevein-containing (hev-) lectins play important roles in stress and pathogenic
responses in plants but cause health concerns in humans. Hev-hololectins contain multiple …