Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Current status of mannose receptor-targeted drug delivery for improved anti-HIV therapy

S Rojekar, AD Gholap, N Togre, P Bhoj… - Journal of Controlled …, 2024 - Elsevier
In the pursuit of achieving better therapeutic outcomes in the treatment of HIV, innovative
drug delivery strategies have been extensively explored. Mannose receptors, which are …

Dual loaded nanostructured lipid carrier of nano-selenium and Etravirine as a potential anti-HIV therapy

S Rojekar, R Pai, LF Abadi, K Mahajan… - International Journal of …, 2021 - Elsevier
There is a dire need for dual-long-acting therapy that could simultaneously target different
stages of the HIV life cycle and providing a dual-prolonged strategy for improved anti-HIV …

[HTML][HTML] Immunomodulatory nanosystems: An emerging strategy to combat viral infections

S Khatun, CL Putta, A Hak, AK Rengan - Biomaterials and Biosystems, 2023 - Elsevier
The viral infection spreads with the assistance of a host. Traditional antiviral therapies
cannot provide long-term immunity against emerging and drug-resistant viral infections …

[HTML][HTML] Impact of conjugation to different lipids on the lymphatic uptake and biodistribution of brush PEG polymers

M Abdallah, L Lin, IK Styles, A Mörsdorf… - Journal of Controlled …, 2024 - Elsevier
Delivery to peripheral lymphatics can be achieved following interstitial administration of
nano-sized delivery systems (nanoparticles, liposomes, dendrimers etc) or molecules that …

Advances in immunological and theranostic approaches of gold nanoparticles–A review

MK Sarangi, S Padhi, G Rath, SS Nanda… - Inorganic Chemistry …, 2023 - Elsevier
The emergence of nanobiotechnology provides an unprecedented opportunity to improve
disease diagnosis and treatment efficacy. Among the various metal-based nano …

[HTML][HTML] Polymer-hybrid nanosystems for antiviral applications: Current advances

DCF Soares, F Poletto, MJ Eberhardt… - Biomedicine & …, 2022 - Elsevier
The emergence of many new viruses in recent times has resulted in a significant scientific
challenge for discovering drugs and vaccines that effectively treat and prevent viral …

Navigating Latency-Inducing Viral Infections: Therapeutic Targeting and Nanoparticle Utilization

A Vasukutty, Y Jang, D Han, H Park… - Biomaterials Research, 2024 - spj.science.org
The investigation into viral latency illuminates its pivotal role in the survival strategies of
diverse viruses, including herpesviruses, HIV, and HPV. This underscores the delicate …

Nanosystems applied to HIV infection: prevention and treatments

MA Macchione, D Aristizabal Bedoya… - International journal of …, 2020 - mdpi.com
Sexually-transmitted infections (STIs) are a global health concern worldwide as they cause
acute diseases, infertility, and significant mortality. Among the bacterial, viral, and parasitic …

Interests of the non-human primate models for HIV cure research

G Terrade, N Huot, C Petitdemange, M Lazzerini… - Vaccines, 2021 - mdpi.com
Non-human primate (NHP) models are important for vaccine development and also
contribute to HIV cure research. Although none of the animal models are perfect, NHPs …