Historically natural compounds and their structural equivalents have significantly contributed
to pharmacotherapy. Sesquiterpenes, the C15-terpenoids are the source of many modern …

Disabilities are estimated to occur in approximately 2% of survivors of traumatic brain injury
(TBI) worldwide, and disability may persist even decades after brain injury. Facilitation or …

It is now well recognized that a bidirectional relationship between gut microbiota and the
brain, referred to as the gut-brain axis, plays a prominent role in maintaining homeostasis …

Farnesoid X receptor (FXR) is a nuclear hormone receptor involved in bile acid synthesis
and homeostasis. Dysfunction of FXR is involved in cholestasis and atherosclerosis. FXR is …

The aim of this study was to investigate the protective effect of naringin, a flavonoid on 3-
Nitropropionic acid (3-NP)-induced neurodegeneration through the modulation of intrinsic …

Neuronal apoptosis occurs as a sequel of oxidative stress associated with various
neuropathies. In this study, we have investigated the protective effect of farnesol, a …

The study was designed to investigate the neuro-protection of lauric acid (LA) on haloperidol
(HPD) induced Parkinson's disease (PkD) rat model. Rats were divided into group A …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease.
Accordingly, 3‐nitropropionic acid (3‐NP) has been found to effectively produce HD‐like …

Gut microbiota perturbation and motor dysfunction have been reported in steatosis patients.
Rats with mild liver damage (MLD) show motor dysfunction mediated by neuroinflammation …

Norepinephrine plays an important role in motor functional recovery after a brain injury
caused by ferrous chloride. Inhibition of norepinephrine release by clonidine is correlated …