Fluorescent nucleoside analogues (FNAs) are structurally diverse mimics of the natural
essentially non-fluorescent nucleosides which have found numerous applications in probing …

Nearly 50 years since its potential as a fluorescent base analogue was first recognized, 2-
aminopurine (2AP) continues to be the most widely used fluorescent probe of DNA structure …

We have found that the efficiency of fluorescence resonance energy transfer between Cy3
and Cy5 terminally attached to the 5′ ends of a DNA duplex is significantly affected by the …

Distinct photophysical behavior of nucleobase adenine and its constitutional isomer, 2-
aminopurine, has been studied by using quantum chemical methods, in particular an …

The native bases of RNA and DNA are prominent examples of the narrow selection of
organic molecules upon which life is based. How did nature “decide” upon these specific …

Abstract 9H‐and 7H‐2, 6‐Diaminopurine (26DAP) photoinduced events in vacuum were
studied at the MS‐CASPT2/cc‐pVDZ level of theory. The S1 1 (ππ* La) state is initially …

DNA base flipping is an important mechanism in molecular enzymology, but its study is
limited by the lack of an accessible and reliable diagnostic technique. A series of crystalline …

Aminopurine is a fluorescent probe widely used to study local dynamics as well as charge
and energy transfer reactions in DNA/RNA. Despite its broad utilization, the nonradiative …

The 4-aminophthalimide C-nucleoside 1 was designed as an isosteric DNA base surrogate,
and a synthetic route to nucleoside 1 together with the 2, 4-diaminopyrimidine-C-nucleoside …

Fluorescent nucleobase analogues are used extensively to probe the structure and
dynamics of nucleic acids. The fluorescence of the adenine analogue 2-aminopurine and …