The lung is an attractive target for drug delivery because of the ease of non-invasive
administration via inhalation, bypassing metabolism in the liver, direct delivery to the …

Dendrimers are well-defined, versatile polymeric architecture with properties resembling
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine …

Used since ancient times especially for the local treatment of pulmonary diseases, lungs and
airways are a versatile target route for the administration of both local and systemic drugs …

Colloidal drug carriers such as liposomes and nanoparticles are able to modify the
distribution of an associated substance. They can therefore be used to improve the …

Many infectious diseases are caused by facultative organisms that are able to survive in
phagocytic cells. The intracellular location of these microorganisms protects them from the …

The study of tropical diseases like leishmaniasis, a parasitic disease, has not received much
attention even though it is the second-largest infectious disease after malaria. As per the …

Leishmaniasis is a vector-borne zoonotic disease caused by protozoan parasites of the
genus Leishmania, which are responsible for numerous clinical manifestations, such as …

Leishmaniasis is one of the six major tropical diseases targeted by the World Health
Organization. It is a life-threatening disease of medical, social and economic importance in …

This paper describes a novel strategy for targeted delivery of amphotericin B (AmB) to
macrophages with muramyl dipeptide (MDP) conjugated multimeric poly …

The present study aimed to develop an optimized dendrimeric delivery system for
amphotericin B (AmB). Fifth-generation (5.0 G) poly (propylene imine)(PPI) dendrimers were …