Anemia is a major source of morbidity and mortality worldwide. Here we review recent
insights into how red blood cells (RBCs) are produced, the pathogenic mechanisms …

Ribosomes are essential components of the protein synthesis machinery. The process of
ribosome biogenesis is well organized and tightly regulated. Recent studies have shown …

Defects in ribosome biogenesis are associated with a group of diseases called the
ribosomopathies, of which Diamond-Blackfan anemia (DBA) is the most studied. Ribosomes …

Abstract Diamond‐Blackfan Anemia (DBA) is characterized by a defect of erythroid
progenitors and, clinically, by anemia and malformations. DBA exhibits an autosomal …

Diamond-Blackfan anemia (DBA) is a genetically and clinically heterogeneous disorder
characterized by erythroid failure, congenital anomalies, and a predisposition to cancer …

Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia caused by a
functional haploinsufficiency of genes encoding for ribosomal proteins. Among these genes …

Diamond-Blackfan anemia (DBA) is a genetic blood disease caused by heterozygous loss-
of-function mutations in ribosomal protein (RP) genes, most commonly RPS19. The …

Gene therapy using hematopoietic stem and progenitor cells is altering the therapeutic
landscape for patients with hematologic, immunologic, and metabolic disorders but has not …

Abstract Diamond Blackfan Anaemia (DBA) is a sporadic inherited anemia with broad
spectrum of anomalies that are presented soon after delivery. It is inherited mainly in …

Diamond Blackfan anemia (DBA) is a congenital disorder with erythroid (Ery) hypoplasia
and tissue morphogenic abnormalities. Most DBA cases are caused by heterozygous null …