Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

Immunomodulation by enteric viruses

L Bernard-Raichon, K Cadwell - Annual Review of Virology, 2023 - annualreviews.org
Enteric viruses display intricate adaptations to the host mucosal immune system to
successfully reproduce in the gastrointestinal tract and cause maladies ranging from …

Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial

JL Vos, B Burman, S Jain, CWR Fitzgerald… - Nature medicine, 2023 - nature.com
Salivary gland cancers (SGCs) are rare, aggressive cancers without effective treatments
when metastasized. We conducted a phase 2 trial evaluating nivolumab (nivo, anti-PD-1) …

Challenges for estimating human norovirus infectivity by viability RT-qPCR as compared to replication in human intestinal enteroids

SQ Wales, A Pandiscia, M Kulka, G Sanchez… - International journal of …, 2024 - Elsevier
Viability RT-qPCR, a molecular detection method combining viability marker pre-treatment
with RT-qPCR, has been proposed to infer infectivity of viruses which is particularly relevant …

Advances in the development of antivirals for rotavirus infection

L Jiang, A Tang, L Song, Y Tong, H Fan - Frontiers in Immunology, 2023 - frontiersin.org
Rotavirus (RV) causes 200,000 deaths per year and imposes a serious burden to public
health and livestock farming worldwide. Currently, rehydration (oral and intravenous) …

Human norovirus efficiently replicates in differentiated 3D-human intestinal enteroids

C Mirabelli, N Santos-Ferreira, MG Gillilland III… - Journal of …, 2022 - Am Soc Microbiol
Human norovirus (HNoV) accounts for one-fifth of all acute viral gastroenteritis worldwide
and an economic burden of~ $60 billion globally. The lack of treatment options against …

[HTML][HTML] Effect of psychological stress on the oral-gut microbiota and the potential oral-gut-brain axis

D Paudel, O Uehara, S Giri, K Yoshida… - … Dental Science Review, 2022 - Elsevier
Psychological stress in a chronic course is implicated in various diseases, such as coronary
artery disease, diabetes, ulcerative colitis, and psychosomatic pain disorders. Commensal …

Persistence of human norovirus (GII) in surface water: Decay rate constants and inactivation mechanisms

LC Kennedy, VP Costantini, KA Huynh… - Environmental …, 2023 - ACS Publications
Human norovirus (HuNoV) is an important cause of acute gastroenteritis and can be
transmitted by water exposures, but its persistence in water is not well understood. Loss of …

[HTML][HTML] Progress in salivary glands: Endocrine glands with immune functions

YF Shang, YY Shen, MC Zhang, MC Lv… - Frontiers in …, 2023 - frontiersin.org
The production and secretion of saliva is an essential function of the salivary glands. Saliva
is a complicated liquid with different functions, including moistening, digestion …

Bioengineered Salivary Gland Microtissues─ A Review of 3D Cellular Models and their Applications

S Pillai, JG Munguia-Lopez, SD Tran - ACS Applied Bio Materials, 2024 - ACS Publications
Salivary glands (SGs) play a vital role in maintaining oral health through the production and
release of saliva. Injury to SGs can lead to gland hypofunction and a decrease in saliva …