Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Conspectus At the heart of synthetic chemistry is the holy grail of predictable catalyst design.
In particular, researchers involved in reaction development in asymmetric catalysis have …

A visible-light-mediated, enantioselective approach to axially chiral alkenes is described.
Starting from a racemic mixture, a major alkene enantiomer is formed due to selective triplet …

Pollution, accidents, and misinformation have earned the pharmaceutical and chemical
industry a poor public reputation, despite their undisputable importance to society …

The widespread success of BINOL-chiral phosphoric acids (CPAs) has led to the
development of several high molecular weight, sterically encumbered variants. Herein, we …

The advent of organocatalysis provided an additional option in every researcher's arsenal,
towards the development of elegant and sustainable protocols for various organic …

Catalysts that control stereochemistry are prized tools in chemical synthesis. When an
effective catalyst is found, it is often explored for other types of reactions, frequently under …

We report the catalytic stereocontrolled synthesis of dinucleotides. We have demonstrated,
for the first time to our knowledge, that chiral phosphoric acid (CPA) catalysts control the …

Desymmetrization of prochiral or meso-substrates bearing pre-existing stereogenic centers
has proven to be a practical and efficient strategy in synthetic chemistry and has attracted …

A catalyst-controlled enantiodivergent bromolactonization of olefinic acids has been
developed. Quinine-derived amino-amides bearing the same chiral core but different achiral …