Newer advances in medical management of glaucoma

N Mohan, A Chakrabarti, N Nazm… - Indian journal of …, 2022 - journals.lww.com
The burden of irreversible vision loss from Glaucoma continues to rise. While the disease
pathogenesis is not well understood, intraocular pressure (IOP) is the only modifiable risk …

Neuroprotective agents in the management of glaucoma

C Nucci, A Martucci, C Giannini, LA Morrone, G Bagetta… - Eye, 2018 - nature.com
Glaucoma is an optic neuropathy, specifically a neurodegenerative disease characterized
by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in …

Natural products: evidence for neuroprotection to be exploited in glaucoma

A Adornetto, L Rombolà, LA Morrone, C Nucci… - Nutrients, 2020 - mdpi.com
Glaucoma, a leading cause of irreversible blindness worldwide, is an optic neuropathy
characterized by the progressive death of retinal ganglion cells (RGCs). Elevated intraocular …

Therapeutic potential of cannabinoids in glaucoma

T Lindner, D Schmidl, L Peschorn, V Pai… - Pharmaceuticals, 2023 - mdpi.com
Glaucoma is a leading cause of irreversible blindness worldwide. To date, intraocular
pressure (IOP) is the only modifiable risk factor in glaucoma treatment, but even in treated …

Cannabinoids in glaucoma patients: The never-ending story

A Passani, C Posarelli, AT Sframeli, L Perciballi… - Journal of clinical …, 2020 - mdpi.com
Glaucoma is one of the principal causes of irreversible blindness worldwide. Yet, intraocular
pressure (IOP) is the main modifiable risk factor for disease progression. In the never-ending …

The endocannabinoid system as a therapeutic target in glaucoma

EA Cairns, WH Baldridge, MEM Kelly - Neural plasticity, 2016 - Wiley Online Library
Glaucoma is an irreversible blinding eye disease which produces progressive retinal
ganglion cell (RGC) loss. Intraocular pressure (IOP) is currently the only modifiable risk …

Innovative Nanoparticles Enhance N-Palmitoylethanolamide Intraocular Delivery

C Puglia, P Blasi, C Ostacolo, E Sommella… - Frontiers in …, 2018 - frontiersin.org
Nanostructured lipid carriers (NLCs) loaded with palmitoylethanolamide (PEA) were
formulated with the aim to enhance ocular bioavailability of PEA, particularly to the back of …

Pharmacological management of ocular hypertension: current approaches and future prospective

C Bucolo, S Salomone, F Drago, M Reibaldi… - Current opinion in …, 2013 - Elsevier
Elevated eye pressure is the main risk factor for glaucoma, and intraocular pressure rises
when the balance between aqueous humor formation and outflow resistance is …

Nutritional supplementation in the treatment of glaucoma: A systematic review

E Loskutova, C O'Brien, I Loskutov, J Loughman - Survey of ophthalmology, 2019 - Elsevier
Current treatment strategies for glaucoma are limited to halting disease progression and do
not restore lost visual function. Intraocular pressure is the main risk factor for glaucoma, and …

Palmitoylethanolamide as adjunctive therapy for autism: Efficacy and safety results from a randomized controlled trial

M Khalaj, A Saghazadeh, E Shirazi… - Journal of psychiatric …, 2018 - Elsevier
Inflammation as well as glutamate excitotoxicity have been proposed to participate in the
propagation of autism. Palmitoylethanolamide (PEA) is an endocannabinoid proven to …