E Herrera-Luis, M Martin-Almeida… - Clinics in chest …, 2024 - chestmed.theclinics.com
Technological advances have accelerated discoveries in human genetics, including risk variant identification, genetic risk prediction, and functional assessment of genetic variation …
Who do you think of when autism is mentioned? Maybe a familiar trope comes to mind: an eccentric white man, perhaps in the vein of The Big Bang Theory's socially naive genius, Dr …
A Espuela-Ortiz, E Martin-Gonzalez, P Poza-Guedes… - Genes, 2023 - mdpi.com
The astounding number of genetic variants revealed in the 15 years of genome-wide association studies of asthma has not kept pace with the goals of translational genomics …
J Perez-Garcia, A Espuela-Ortiz… - Journal of Allergy and …, 2023 - Elsevier
Background The upper-airway microbiome is involved in asthma exacerbations despite inhaled corticosteroid (ICS) treatment. Although human genetics regulates microbiome …
Adverse drug reactions (ADRs) are a significant public health concern and a leading cause of hospitalization; they are estimated to be the fourth leading cause of death and increasing …
Personalized medicine, an approach to care in which individual characteristics are used for targeting interventions and maximizing health outcomes, is rapidly becoming a reality for …
E Herrera-Luis, E Forno, JC Celedón… - … allergology & clinical …, 2022 - pmc.ncbi.nlm.nih.gov
The clinical and socioeconomic burden of asthma exacerbations (AEs) represents a major public health problem. In the last four years, there has been an increase in ethnic diversity in …
M Khare, S Piparia, KG Tantisira - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Asthma is a heterogeneous, multifactorial disease with multiple genetic and environmental risk factors playing a role in pathogenesis and therapeutic response …
A Lawton, A Stephenson-Allen, A Whitehouse… - Paediatric Respiratory …, 2023 - Elsevier
Asthma is now the commonest chronic disease of childhood, but not all children with asthma receive equivalent standards of medical care which influences their clinical outcomes. In this …