Health Disparities: Interventions for Pulmonary Disease–A Narrative Review

LJ Harper, P Kidambi, JM Kirincich, JD Thornton… - Chest, 2023 - Elsevier
There is expansive literature documenting the presence of health disparities, but there are
disproportionately few studies describing interventions to reduce disparity. In this narrative …

Asthma—Genomic Advances Toward Risk Prediction

E Herrera-Luis, M Martin-Almeida… - Clinics in chest …, 2024 - chestmed.theclinics.com
Technological advances have accelerated discoveries in human genetics, including risk
variant identification, genetic risk prediction, and functional assessment of genetic variation …

Shifting stigma about autistic young people

J Den Houting, M Botha, E Cage, DR Jones… - The Lancet Child & …, 2021 - thelancet.com
Who do you think of when autism is mentioned? Maybe a familiar trope comes to mind: an
eccentric white man, perhaps in the vein of The Big Bang Theory's socially naive genius, Dr …

Genomics of Treatable Traits in Asthma

A Espuela-Ortiz, E Martin-Gonzalez, P Poza-Guedes… - Genes, 2023 - mdpi.com
The astounding number of genetic variants revealed in the 15 years of genome-wide
association studies of asthma has not kept pace with the goals of translational genomics …

[HTML][HTML] Human genetics influences microbiome composition involved in asthma exacerbations despite inhaled corticosteroid treatment

J Perez-Garcia, A Espuela-Ortiz… - Journal of Allergy and …, 2023 - Elsevier
Background The upper-airway microbiome is involved in asthma exacerbations despite
inhaled corticosteroid (ICS) treatment. Although human genetics regulates microbiome …

A review of real-world evidence on preemptive pharmacogenomic testing for preventing adverse drug reactions: a reality for future health care

S Chenchula, S Atal, CRS Uppugunduri - The Pharmacogenomics …, 2024 - nature.com
Adverse drug reactions (ADRs) are a significant public health concern and a leading cause
of hospitalization; they are estimated to be the fourth leading cause of death and increasing …

Pharmacogenomics: A step forward precision medicine in childhood asthma

G Ferrante, S Fasola, V Malizia, A Licari, G Cilluffo… - Genes, 2022 - mdpi.com
Personalized medicine, an approach to care in which individual characteristics are used for
targeting interventions and maximizing health outcomes, is rapidly becoming a reality for …

[HTML][HTML] Asthma exacerbations: the genes behind the scenes

E Herrera-Luis, E Forno, JC Celedón… - … allergology & clinical …, 2022 - pmc.ncbi.nlm.nih.gov
The clinical and socioeconomic burden of asthma exacerbations (AEs) represents a major
public health problem. In the last four years, there has been an increase in ethnic diversity in …

Pharmacogenetics of childhood uncontrolled asthma

M Khare, S Piparia, KG Tantisira - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Asthma is a heterogeneous, multifactorial disease with multiple genetic and
environmental risk factors playing a role in pathogenesis and therapeutic response …

Racial bias in recruitment to clinical trials on paediatric asthma

A Lawton, A Stephenson-Allen, A Whitehouse… - Paediatric Respiratory …, 2023 - Elsevier
Asthma is now the commonest chronic disease of childhood, but not all children with asthma
receive equivalent standards of medical care which influences their clinical outcomes. In this …