[HTML][HTML] Role of natural compounds modulating Heme catabolic pathway in gut, liver, cardiovascular, and brain diseases

S Jayanti, L Vitek, CD Verde, JP Llido, C Sukowati… - Biomolecules, 2024 - mdpi.com
The crucial physiological process of heme breakdown yields biliverdin (BV) and bilirubin
(BR) as byproducts. BV, BR, and the enzymes involved in their production (the “yellow …

Alpha-Lipoic acid alleviates imidacloprid-induced neuro-behavioral deficits in rats via Nrf2/HO-1 pathway

M Nema, BJ Dutta, S Singh - Toxicology Mechanisms and Methods, 2024 - Taylor & Francis
Imidacloprid (IMI), a widely used pesticide in agriculture and a potential food contaminant,
poses significant health concerns. This study sought to comprehensively evaluate its …

Pharmacotherapeutic potential of malvidin to cure imidacloprid induced hepatotoxicity via regulating PI3K/AKT, Nrf-2/Keap-1 and NF-κB pathway

H Edwards, W Mustfa, S Tehreem… - Food and Chemical …, 2024 - Elsevier
Imidacloprid (IMI) is one of the top-notch insecticides which adversely affects the body
organs including liver. Malvidin (MAL) is a natural flavonoid which exhibits a wide range of …

Withania somnifera (L.) Dunal ameliorates imidacloprid induced neurotoxicity: Inhibition of oxidative stress, apoptosis and downregulation of glial fibrillary acidic …

S Soujanya, M Lakshman, D Madhuri, AG Reddy… - 2024 - nopr.niscpr.res.in
In agricultural farming, neonicotinoid insecticides are used to control insect pests on
agricultural crops and ectoparasitic arthropods on animals. Here, we evaluated the oral …

MODELING A PARKINSON'S DISEASE LIKE STATE IN ZEBRAFISH LARVAE UTILIZING 6-HYDROXYDOPAMINE

A Romero - 2023 - scholarworks.uttyler.edu
Abstract Parkinson's' disease (PD) is a neurodegenerative disorder characterized by the
loss of midbrain dopaminergic (mDA) neurons that currently has no cure. It is primarily …