The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by
Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant …

Parkinson's disease is a progressive neurodegenerative disorder characterized by the
degeneration of midbrain nigral dopaminergic neurons. Although its etiology remains …

The role of individual factors in behavioural neuroscience is an important, but still neglected
area of research. The present review aims to give, first, an outline of the most elaborated …

Emerging evidence indicates that certain behavioral traits, such as anxiety, are associated
with the development of depression-like behaviors after exposure to chronic stress …

We demonstrate that the rate of extracellular signal-related kinase phosphorylation (P-
ERK1, 2/Total-ERK1, 2) in the amygdala is negatively and independently associated with …

Glutamatergic dysfunction has been implicated in the neurodegeneration seen in
Parkinson's disease (PD). Sub-chronic intraperitoneal injection with d-cycloserine (DCS), a …

Emotional changes, impairment of object recognition, and neuroinflammation are seen in
Parkinson's disease with dementia (PDD). Here, we show that bilateral infusion of 1-methyl …

The role of individual factors in behavioral neuroscience is an important, but still neglected,
area of research. For example, the Elevated Plus-Maze Test has been one of the most used …

Anxiety disorders have a high prevalence, and despite the substantial advances in the
psychological treatment of anxiety, relapse is still a common problem. One approach to …

Sarcosine, an N-methyl-d-aspartate receptor enhancer, can improve depression-like
behavior in rodent models and depression in humans. We found that a single dose of …