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24, 2004, provisional application No. 60/546,277. 5,409,811 A 4/1995 Tabor et al. filed on …

(54) METHODS AND APPARATUS FOR 4,962,037 A 10/1990 Jett et al. ANALYZING
POLYNUCLEOTIDE 4,971,903 A 11/1990 Hyman SEQUENCES BY ASYNCHRONOUS …

4.703, 705 A 12/1988 SN, 6, 024925 A 2/2000 Little et al. 4811218 A 3/1989 Hunkapiller et
al. 6,043,080 A* 3/2000 Lipshutz et al............ 422/68.1 4863849 A 9/1989 Melamede …

I: Flow Channel r I 2 Control Channel locations along the rotary micro? uidic channel at
Which temperature is regulated. Solution can be repeatedly passed through the temperature …

(54) METHODS AND APPARATUS FOR 5,375,979 A 12/1994 Trah ANALYZING
POLYNUCLEOTIDE 5,376,252 A 12/1994 Ekstrom SEQUENCES 5,405,747 A 4/1995 …

Embodiments of the present invention are directed to methods and devices/systems for
amplifying genetic material and may include providing a water-in-oil emulsion in a …

A variety of elastomeric-based microfluidic devices and methods for using and
manufacturing such devices are provided. Certain of the devices have arrays of reaction …

The present invention relates to a novel method for analyzing nucleic acid sequences based
on real-time detection of DNA poly-merase-catalyzed incorporation of each of the four …

The technology described herein generally relates to systems for extracting polynucleotides
from multiple samples, particularly from biological samples, and additionally to systems that …

US9040288B2 - Integrated system for processing microfluidic samples, and method of
using the same - Google Patents US9040288B2 - Integrated system for processing …