Ferroptosis is a form of regulatory cell death distinct from caspase-dependent apoptosis and
plays an important role in life entities. Since ferroptosis involves a variety of complex …

The human brain consumes 20% of the total basal oxygen (O 2) budget to support ATP
intensive neuronal activity. Without sufficient O 2 to support ATP demands, neuronal activity …

The microbiota-gut-brain axis has emerged as a novel target in depression, a disorder with
low treatment efficacy. However, the field is dominated by underpowered studies focusing …

Background Iron is essential for many types of biological processes. However, excessive
iron can be cytotoxic and can lead to many diseases. Since ferroptosis, which is an iron …

Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Intracerebral hemorrhage (ICH) causes high mortality and morbidity, but our knowledge of
post-ICH neuronal death and related mechanisms is limited. In this study, we first …

Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …

There are several interrelated mechanisms involving iron, dopamine, and neuromelanin in
neurons. Neuromelanin accumulates during aging and is the catecholamine-derived …

Incidence of intracerebral hemorrhage (ICH) and brain iron accumulation increases with
age. Excess iron accumulation in brain tissues post‐ICH induces oxidative stress and …

In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …