Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Targeted drug delivery has been extensively studied in the last decade, whereas both
passive and active targeting strategies still face many challenges, such as off‐target drug …

Photocages are light-sensitive chemical protecting groups that give investigators control
over activation of biomolecules using targeted light irradiation. A compelling application of …

Protein‐based drugs have shown unique advantages to treat various diseases in recent
years. However, most protein therapeutics in clinical use are limited to extracellular targets …

Photoremovable protecting groups (PPGs) have become significant optical molecular tools
in modern biomedicine. The unique property of photorelease allows noninvasively …

Background Photoresponsive drug delivery can achieve spatiotemporal control of drug
accumulation at desired sites. Long-wavelength light is preferable owing to its deep tissue …

Photoresponsive drug release systems can enhance drug accumulation at the sites where
light is applied. Nowadays, the photocleavable groups used in the systems usually require …

Photoresponsive drug delivery systems (PDDSs) have emerged as a promising toolbox for
drug delivery, offering precise control over the site, duration, and dosage of light‐triggered …

The blockade of PD‐1/PD‐L1, which serves to “release the brake” of tumor immunity,
represents a promising approach for treating various malignancies. However, the systemic …

Self-assembly is a simple yet reliable method for constructing nanoscale drug delivery
systems. Photoactivatable prodrugs enable controllable drug release from nanocarriers at …