The subgingival crevice harbors diverse microbial communities. Shifts in the composition of
these communities occur with the development of gingivitis and periodontitis, which are …

Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue
in the periodontal region. Although dysbiosis of the local microbial community initiates local …

Inflammasomes are a group of multimolecular intracellular complexes assembled around
several innate immune proteins. Recognition of a diverse range of microbial, stress and …

Inflammation is characterized by a biphasic cycle consisting initially of a proinflammatory
phase that is subsequently resolved by anti-inflammatory processes. Interleukin-1β (IL-1β) is …

The dance between microbes and the immune system takes place in all biological systems,
including the human body, but this interaction is especially complex in the primary gateway …

Periodontitis, one of the most common infectious diseases in humans, is characterized by
inflammation of the periodontal tissue and subsequent destruction of the alveolar bone …

Periodontitis is a chronic inflammatory disease caused by the bacteria infection in dental
plaque, which can lead to gingival recession and tooth loss, seriously endangering human …

Biofilm bacteria co‐evolve and reach a symbiosis with the host on the gingival surface. The
disruption of the homeostatic relationship between plaque bacteria and the host can initiate …

Recent advances in human genomics and the advent of molecular medicine have
catapulted our ability to characterize human and health and disease. Scientists and …

Although mesenchymal stem cell-derived exosomes (MSC-exos) have been shown to have
therapeutic effects in experimental periodontitis, their drawbacks, such as low yield and …