L Xiao, DG Harrison - Canadian Journal of Cardiology, 2020 - Elsevier
For more than 50 years, evidence has accumulated that inflammation contributes to the pathogenesis of hypertension. Immune cells have been observed in vessels and kidneys of …
TJ Guzik, R Nosalski, P Maffia… - Nature Reviews …, 2024 - nature.com
Hypertension is a global health problem, with> 1.3 billion individuals with high blood pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …
Inflammasomes are components of the innate immune response that have recently emerged as crucial controllers of tissue homeostasis. In particular, the nucleotide-binding domain …
E Bajwa, A Klegeris - Neural Regeneration Research, 2022 - journals.lww.com
Alzheimer's disease, the most common type of dementia among older adults, currently cannot be prevented or effectively treated. Only a very small percentage of Alzheimer's …
JP Van Beusecum, H Moreno… - Journal of human …, 2022 - nature.com
Emerging evidence has supported a role of inflammation and immunity in the genesis of hypertension. In humans and experimental models of hypertension, cells of the innate and …
A Nashiry, S Sarmin Sumi, S Islam… - Briefings in …, 2021 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals that have hypertension or cardiovascular comorbidities have an elevated risk of serious …
Significance: Salt sensitivity of blood pressure (SSBP) is an independent risk factor for mortality and morbidity due to cardiovascular disease, and disproportionately affects blacks …
Heart failure with preserved ejection fraction (HFpEF) now accounts for the majority of new heart failure diagnoses and continues to increase in prevalence in the United States …
VA Simão, L Ferder, W Manucha… - Current Hypertension …, 2022 - Springer
Abstract Purpose of Review This review summarizes the involvement of inflammaging in vascular damage with focus on the epigenetic mechanisms by which inflammaging-induced …