Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome

I Khan, N Ullah, L Zha, Y Bai, A Khan, T Zhao, T Che… - Pathogens, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …

[HTML][HTML] Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?

GL Hold, M Smith, C Grange, ER Watt… - World journal of …, 2014 - ncbi.nlm.nih.gov
Our understanding of the microbial involvement in inflammatory bowel disease (IBD)
pathogenesis has increased exponentially over the past decade. The development of newer …

The intestinal microbiota in inflammatory bowel disease

C Becker, MF Neurath, S Wirtz - ILAR journal, 2015 - academic.oup.com
The intestinal microbiota has important metabolic and host-protective functions. Conversely
to these beneficial functions, the intestinal microbiota is thought to play a central role in the …

[HTML][HTML] Mycobacterium avium subspecies paratuberculosis causes Crohn's disease in some inflammatory bowel disease patients

SA Naser, SR Sagramsingh, AS Naser… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Crohn's disease (CD) is a chronic inflammatory condition that plagues millions all over the
world. This debilitating bowel disease can start in early childhood and continue into late …

Pathogenesis, Molecular Genetics, and Genomics of Mycobacterium avium subsp. paratuberculosis, the Etiologic Agent of Johne's Disease

G Rathnaiah, DK Zinniel, JP Bannantine… - Frontiers in veterinary …, 2017 - frontiersin.org
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of Johne's
disease in ruminants causing chronic diarrhea, malnutrition, and muscular wasting …

Bacteriophages in gut samples from pediatric Crohn's disease patients: metagenomic analysis using 454 pyrosequencing

J Wagner, J Maksimovic, G Farries… - Inflammatory bowel …, 2013 - academic.oup.com
Background The role of bacteriophage in Crohn's disease (CD) is unknown. This study
investigated the abundance of phages in ileal and colonic samples from pediatric CD …

The role of bacteria and pattern-recognition receptors in Crohn's disease

SM Man, NO Kaakoush, HM Mitchell - Nature reviews Gastroenterology …, 2011 - nature.com
Crohn's disease is widely regarded as a multifactorial disease, and evidence from human
and animal studies suggests that bacteria have an instrumental role in its pathogenesis …

Crohn's disease and the mycobacterioses: a quarter century later. Causation or simple association?

RJ Chiodini, WM Chamberlin, J Sarosiek… - Critical reviews in …, 2012 - Taylor & Francis
It has been more than 25 years since Mycobacterium paratuberculosis was first proposed as
an etiologic agent in Crohn's disease based on the isolation of this organism from several …

Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease

P De Cruz, L Prideaux, J Wagner, SC Ng… - Inflammatory bowel …, 2012 - academic.oup.com
The enteric bacterial flora play a key role in maintaining health. Inflammatory bowel disease
is associated with quantitative and qualitative alterations in the microbiota. Early …

Case definition terminology for paratuberculosis (Johne's disease)

RJ Whittington, DJ Begg, K De Silva, AC Purdie… - BMC veterinary …, 2017 - Springer
Paratuberculosis (Johne's disease) is an economically significant condition caused by
Mycobacterium avium subsp. paratuberculosis. However, difficulties in diagnosis and …