[HTML][HTML] A critical review on quercetin bioflavonoid and its derivatives: scope, synthesis, and biological applications with future prospects

S Dhanaraj - Arabian Journal of Chemistry, 2023 - Elsevier
Lifestyle is an important factor in health, and researchers are trying to see the adverse effect
on human health of a change in lifestyle. Many people follow unhealthy lifestyles, which …

Quercetin as a JAK–STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases

H Zalpoor, M Nabi-Afjadi, R Forghaniesfidvajani… - Cellular & molecular …, 2022 - Springer
The Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is
involved in many immunological processes, including cell growth, proliferation …

[HTML][HTML] Focus on immune checkpoint PD-1/PD-L1 pathway: New advances of polyphenol phytochemicals in tumor immunotherapy

K Liu, Q Sun, Q Liu, H Li, W Zhang, C Sun - Biomedicine & …, 2022 - Elsevier
The rise of cancer immunotherapy, particularly the use of immune checkpoint inhibitors
(ICIs), has significantly changed the clinical treatment paradigm for patients with cancer. The …

Anticancer and apoptosis inducing potential of quercetin against a wide range of human malignancies

M Shahbaz, H Naeem, U Momal, M Imran… - … Journal of Food …, 2023 - Taylor & Francis
Quercetin, a flavonoid, is a dietary component that has attracted the attention of dietitians
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …

Analysis of the mechanism of action of quercetin in the treatment of hyperlipidemia based on metabolomics and intestinal flora

T Wang, L Liu, J Deng, Y Jiang, X Yan, W Liu - Food & function, 2023 - pubs.rsc.org
Hyperlipidemia (HLP) is one of the main factors leading to cardiovascular diseases.
Quercetin (QUE) is a naturally occurring polyhydroxy flavonoid compound that has a wide …

Pancreatic ductal adenocarcinoma and nutrition: Exploring the role of diet and gut health

P Gualtieri, R Cianci, G Frank, E Pizzocaro… - Nutrients, 2023 - mdpi.com
The incidence of pancreatic cancer is increasing worldwide. The most common form is
represented by pancreatic ductal adenocarcinoma (PDAC) which has been shown to be …

A pHe sensitive nanodrug for collaborative penetration and inhibition of metastatic tumors

M Huo, J Zhou, H Wang, Y Zheng, Y Tong… - Journal of Controlled …, 2022 - Elsevier
Current chemotherapies for metastatic tumors are seriously restricted by limited drug
infiltration and deficient disturbance of metastasis-associated complex pathways involving …

Phytochemicals for the prevention and treatment of pancreatic cancer: Current progress and future prospects

N Casarcia, P Rogers, E Guld, S Iyer… - British Journal of …, 2023 - Wiley Online Library
Pancreatic cancer is the third leading cause of cancer‐related deaths in the United States,
owing to its aggressive nature and suboptimal treatment options, emphasizing the need for …

Therapeutic potential of flavonoids from traditional Chinese medicine in pancreatic cancer treatment

Q Wan, Q Ren, S Qiao, A Lyu, X He, F Li - Frontiers in Nutrition, 2024 - frontiersin.org
Pancreatic cancer (PC) is a highly aggressive malignancy with rising mortality rates globally.
Its diagnosis is often challenging due to its asymptomatic nature in the early stages …

Quercetin improves pancreatic cancer chemo‐sensitivity by regulating oxidative‐inflammatory networks

Y Hu, R Li, J Jin, Y Wang, R Ma - Journal of Food Biochemistry, 2022 - Wiley Online Library
Chemotherapy is the main method for controlling pancreatic cancer metastasis but the
prevalent chemotherapy resistance limits its utilization. The response of oxidation and …