Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity

X Zeng, Y Xie, Y Liu, S Long, Z Mo - Clinica chimica acta, 2020 - Elsevier
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease
characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic …

Obesity as disruptor of the female fertility

E Silvestris, G De Pergola, R Rosania… - Reproductive Biology and …, 2018 - Springer
Both obesity and overweight are increasing worldwide and have detrimental influences on
several human body functions including the reproductive health. In particular, obese women …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

[PDF][PDF] Focus on obesity

CJ Brewer, AH Balen - Reproduction, 2010 - edisciplinas.usp.br
Whilst many multiparous women are obese (body mass index O30 kg/m2), obesity has been
associated with impaired fecundity; however, the mechanism which links obesity to reduced …

The deep correlation between energy metabolism and reproduction: a view on the effects of nutrition for women fertility

R Fontana, S Della Torre - Nutrients, 2016 - mdpi.com
In female mammals, mechanisms have been developed, throughout evolution, to integrate
environmental, nutritional and hormonal cues in order to guarantee reproduction in …

Anti-mullerian hormone as a predictor of time to menopause in late reproductive age women

EW Freeman, MD Sammel, H Lin… - The Journal of Clinical …, 2012 - academic.oup.com
Context: Anti-Mullerian hormone (AMH) has emerged as a marker of ovarian reserve and a
possible surrogate measure of reproductive aging. Objective: The aim of the study was to …

Adiponectin action from head to toe

K Brochu-Gaudreau, C Rehfeldt, R Blouin, V Bordignon… - Endocrine, 2010 - Springer
Adiponectin, the most abundant protein secreted by white adipose tissue, is known for its
involvement in obesity-related disorders such as insulin resistance, type 2 diabetes mellitus …

Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome

SF de Medeiros, RJ Rodgers… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Metabolic and endocrine alterations in women with polycystic ovary
syndrome (PCOS) affect adipose tissue mass and distribution. PCOS is characterised by …

Sheep models of polycystic ovary syndrome phenotype

V Padmanabhan, A Veiga-Lopez - Molecular and cellular endocrinology, 2013 - Elsevier
Polycystic ovary syndrome (PCOS) is a fertility disorder affecting 5–7% of reproductive-aged
women. Women with PCOS manifest both reproductive and metabolic defects. Several …

Mechanisms of adiponectin action in fertility: an overview from gametogenesis to gestation in humans and animal models in normal and pathological conditions

A Barbe, A Bongrani, N Mellouk, A Estienne… - International journal of …, 2019 - mdpi.com
Adiponectin is the most abundant plasma adipokine. It mainly derives from white adipose
tissue and plays a key role in the control of energy metabolism thanks to its insulin …