mRECIST for HCC: performance and novel refinements

JM Llovet, R Lencioni - Journal of hepatology, 2020 - Elsevier
Summary In 2010, modified RECIST (mRECIST) criteria were proposed as a way of
adapting the RECIST criteria to the particularities of hepatocellular carcinoma (HCC). We …

Trial design and endpoints in hepatocellular carcinoma: AASLD consensus conference

JM Llovet, A Villanueva, JA Marrero, M Schwartz… - …, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide.(1, 2) This neoplasm has some unique characteristics. It occurs in most cases …

Liposomal irinotecan plus fluorouracil and leucovorin versus fluorouracil and leucovorin for metastatic biliary tract cancer after progression on gemcitabine plus …

C Yoo, K Kim, JH Jeong, I Kim, MJ Kang… - The Lancet …, 2021 - thelancet.com
Background The prognosis of patients with advanced biliary tract cancer who have
progressed on gemcitabine plus cisplatin is dismal. We aimed to investigate the efficacy and …

The financial burden and distress of patients with cancer: understanding and stepping‐up action on the financial toxicity of cancer treatment

PM Carrera, HM Kantarjian… - CA: a cancer journal for …, 2018 - Wiley Online Library
Abstract “Financial toxicity” has now become a familiar term used in the discussion of cancer
drugs, and it is gaining traction in the literature given the high price of newer classes of …

Codon-specific KRAS mutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer

J van de Haar, X Ma, SN Ooft, PW van der Helm… - Nature Medicine, 2023 - nature.com
Genomics has greatly improved how patients with cancer are being treated; however,
clinical-grade genomic biomarkers for chemotherapies are currently lacking. Using whole …

Pancreatic adenocarcinoma, version 2.2017, NCCN clinical practice guidelines in oncology

MA Tempero, MP Malafa, M Al-Hawary… - Journal of the National …, 2017 - jnccn.org
Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-
quality multiphase imaging can help to preoperatively distinguish between patients eligible …

Association of PD-L1 expression and other variables with benefit from immune checkpoint inhibition in advanced gastroesophageal cancer: systematic review and …

HH Yoon, Z Jin, O Kour, LAK Fonkoua, K Shitara… - JAMA …, 2022 - jamanetwork.com
Importance Approval by the US Food and Drug Administration of immune checkpoint
inhibition (ICI) for advanced gastroesophageal cancer (aGEC) irrespective of PD-L1 status …

Primary tumor resection plus chemotherapy versus chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases …

Y Kanemitsu, K Shitara, J Mizusawa… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE It remains controversial whether primary tumor resection (PTR) before
chemotherapy improves survival in patients with colorectal cancer (CRC) with asymptomatic …

Systemic therapy for stage IV non–small-cell lung cancer: American Society of Clinical Oncology clinical practice guideline update

N Hanna, D Johnson, S Temin, S Baker Jr… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Provide evidence-based recommendations updating the 2015 ASCO guideline on
systemic therapy for patients with stage IV non–small-cell lung cancer (NSCLC). Methods …

[HTML][HTML] A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: the European …

NI Cherny, R Sullivan, U Dafni, JM Kerst, A Sobrero… - Annals of …, 2015 - Elsevier
The value of any new therapeutic strategy or treatment is determined by the magnitude of its
clinical benefit balanced against its cost. Evidence for clinical benefit from new treatment …