EA Masters, RP Trombetta, KL de Mesy Bentley… - Bone research, 2019 - nature.com
Osteomyelitis is a devastating disease caused by microbial infection of bone. While the frequency of infection following elective orthopedic surgery is low, rates of reinfection are …
S Sánchez-Salcedo, A García, A González-Jiménez… - Acta Biomaterialia, 2023 - Elsevier
The development of new biomaterials for bone tissue regeneration with high bioactivity abilities and antibacterial properties is being intensively investigated. We have synthesized …
EM Schwarz, J Parvizi, T Gehrke, A Aiyer… - Journal of …, 2019 - Wiley Online Library
Musculoskeletal infections (MSKI) remain the bane of orthopedic surgery, and result in grievous illness and inordinate costs that threaten healthcare systems. As prevention …
Microbes have remarkable capabilities to attach to the surface of implanted medical devices and form biofilms that adversely impact device function and increase the risk of multidrug …
KL Urish, JE Cassat - Infection and immunity, 2020 - Am Soc Microbiol
Osteomyelitis, or inflammation of bone, is most commonly caused by invasion of bacterial pathogens into the skeleton. Bacterial osteomyelitis is notoriously difficult to treat, in part …
Chronic bone infection is considered as one of the most problematic biofilm‐related infections. Its recurrent and resistant nature, high morbidity, prolonged hospitalization, and …
EG Di Domenico, A Oliva, M Guembe - Microorganisms, 2022 - mdpi.com
Biofilm is the trigger for the majority of infections caused by the ability of microorganisms to adhere to tissues and medical devices. Microbial cells embedded in the biofilm matrix are …
Abstract Purpose of Review Staphylococcus aureus is the primary pathogen responsible for osteomyelitis, which remains a major healthcare burden. To understand its dominance, here …
MN Gamaletsou, B Rammaert, B Brause… - Clinical Microbiology …, 2022 - Am Soc Microbiol
Osteoarticular mycoses are chronic debilitating infections that require extended courses of antifungal therapy and may warrant expert surgical intervention. As there has been no …