X Wang, S Wu, TYD Tang, L Tian - Trends in Chemistry, 2022 - cell.com
An ongoing grand challenge in bottom-up synthetic biology is designing and constructing synthetic cells with life-like properties. Despite the significant advances, even the most …
Reconstitution and simulation of cellular motility in microcompartmentalized colloidal objects have important implications for microcapsule-based remote sensing, environmentally …
In contrast to Brownian transport, the active motility of microbes, cells, animals and even humans often follows another random process known as truncated Lévy walk,. These …
BM Bensel, SB Previs, C Bookwalter, KM Trybus… - Proceedings of the …, 2024 - pnas.org
Kinesin-1 ensembles maneuver vesicular cargoes through the three-dimensional (3D) intracellular microtubule (MT) network. To define how such cargoes navigate MT …
R Grover, J Fischer, FW Schwarz… - Proceedings of the …, 2016 - National Acad Sciences
In eukaryotic cells, membranous vesicles and organelles are transported by ensembles of motor proteins. These motors, such as kinesin-1, have been well characterized in vitro as …
Microtubules are hollow, cylindrical polymers of the protein α, β tubulin, that interact mechanochemically with a variety of macromolecules. Due to their mechanically robust …
Q Li, JT Ferrare, J Silver, JO Wilson… - Proceedings of the …, 2023 - National Acad Sciences
Intracellular cargos are often membrane-enclosed and transported by microtubule-based motors in the presence of microtubule-associated proteins (MAPs). Whereas increasing …
SR Nelson, KM Trybus… - Proceedings of the …, 2014 - National Acad Sciences
Myosin Va is an actin-based molecular motor responsible for transport and positioning of a wide array of intracellular cargoes. Although myosin Va motors have been well …
Microtubules are hollow cylindrical polymers composed of the highly negatively-charged (~ 23e), high dipole moment (1750 D) protein α, β-tubulin. While the roles of microtubules in …