Substance use disorders (SUD) are a serious public health concern globally. Existing treatment platforms suffer from a lack of effectiveness. The development of immunotherapies …
Among vaccines aimed at treating substance use disorders, those targeting opioids present several unique medication development challenges. 1) Opioid overdose is a common …
F Baruffaldi, AH Kelcher, M Laudenbach… - Molecular …, 2018 - ACS Publications
Vaccines may offer a new treatment strategy for opioid use disorders and opioid-related overdoses. To speed translation, this study evaluates opioid conjugate vaccines containing …
Importance Novel treatments for opioid use disorder (OUD) are needed to address both the ongoing opioid epidemic and long-standing barriers to existing OUD treatments that target …
TR Kosten - American Journal of Psychiatry, 2024 - Am Psychiatric Assoc
Substance use disorders (SUD) present a worldwide challenge with few effective therapies except for the relative efficacy of opioid pharmacotherapies, despite limited treatment …
Introduction Development and implementation of effective treatments for opioid use disorder (OUD) and prevention of overdose are urgent public health needs. Though existing …
B Kinsey - Therapeutic advances in vaccines, 2014 - journals.sagepub.com
Drug addiction is a serious problem worldwide. One therapy being investigated is vaccines against drugs of abuse. The antibodies elicited against the drug can take up the drug and …
This study focused on formulating conjugate vaccines targeting oxycodone and heroin for technology transfer, good manufacturing practice (GMP), and clinical evaluation. Lead …
A Carfora, P Cassandro, A Feola, F La Sala… - Journal of bioethical …, 2018 - Springer
Different immunotherapeutic approaches are in the pipeline for the treatment of drug dependence.“Drug vaccines” aim to induce the immune system to produce antibodies that …