Heart morphogenesis is a complex and dynamic process that has captivated researchers for
almost a century. This process involves three main stages, during which the heart …

With the explosion of gene editing tools in recent years, there has been a much greater
demand for mouse embryo phenotyping, and traditional methods such as histology and …

Application of optical imaging in developmental biology marks an exciting frontier in
biomedical optics. Optical resolution and imaging depth allow for investigation of growing …

Myocardial infarction (MI) leads to cardiomyocyte loss, impaired cardiac function, and heart
failure. Molecular genetic analyses of myocardium in mouse models of ischemic heart …

The embryonic heart is an active and developing organ. Genetic studies in mouse models
have generated great insight into normal heart development and congenital heart defects …

In vertebrates, the coordinated beat of the early heart tube drives cardiogenesis and
supports embryonic growth. How the heart pumps at this valveless stage marks a fascinating …

Neural tube closure is a critical feature of central nervous system morphogenesis during
embryonic development. Failure of this process leads to neural tube defects, one of the most …

A single‐channel high‐resolution cross‐polarization (CP) optical coherence tomography
(OCT) system is presented for multicontrast imaging of human myocardium in one‐shot …

Significance: Understanding how the valveless embryonic heart pumps blood is essential to
elucidate biomechanical cues regulating cardiogenesis, which is important for the …

Efficient separation of blood and cardiac wall in the beating embryonic heart is essential and
critical for experiment‐based computational modelling and analysis of early‐stage cardiac …