Roles of endoplasmic reticulum stress in the pathophysiology of polycystic ovary syndrome

H Koike, M Harada, A Kusamoto, Z Xu… - Frontiers in …, 2023 - frontiersin.org
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
reproductive-age women, affecting up to 15% of women in this group, and the most common …

The Effects of Plant-Derived Phytochemical Compounds and Phytochemical-Rich Diets on Females with Polycystic Ovarian Syndrome: A Scoping Review of Clinical …

GN Chavez, K Jaworsky, A Basu - International Journal of Environmental …, 2023 - mdpi.com
Polycystic ovarian syndrome (PCOS) is an endocrine condition that impacts nutritional
status, metabolic, and hormonal function in females of reproductive age. This condition is …

Polycystic ovary syndrome and related inflammation in radiomics; relationship with patient outcome

CY Zheng, YX Yu, X Bai - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) refers to a condition that often has 'poly'liquid containing
sacks around ovaries. It affects reproductive-aged females giving rise to menstrual and …

Curcumin and gallic acid have a synergistic protective effect against ovarian surface epithelium and follicle reserve damage caused by autologous intraperitoneal …

KB Baki, T Sapmaz, K Sevgin, S Topkaraoglu… - … -Research and Practice, 2024 - Elsevier
The objective of this study to examine the effects of curcumin and gallic acid use against
oxidative stress damage in the autologous intraperitoneal ovarian transplantation model …

Follicle prediction for polycystic ovary syndrome diagnosis from ovarian ultrasound images using cnn

S Prasher, L Nelson - 2023 10th International Conference on …, 2023 - ieeexplore.ieee.org
polycystic ovarian syndrome (PCOS) is the most common hormone related disorder
worldwide. PCOS is caused by numerous tiny fluid-filled sacs called follicles, which are …

Map4k4 is up-regulated and modulates granulosa cell injury and oxidative stress in polycystic ovary syndrome via activating JNK/c-JUN pathway: An experimental …

L Ding, L Jiang, Z Xing, H Dai, J Wei - International Immunopharmacology, 2023 - Elsevier
The regulatory mechanism on granulosa cells (GCs) oxidative injury is becoming
increasingly important in polycystic ovary syndrome (PCOS) studies. Serine/threonine …

Curcumin's Dose-Dependent Attenuation of Gastric Cancer Cell Progression Via the PI3K Pathway Blockade

G Xi, Q Dong, B Yang, D Jiao, S Khan - Dose-Response, 2023 - journals.sagepub.com
Background: Gastric cancer stands as a primary cause of cancer-related deaths worldwide,
making the discovery of new therapeutic agents essential for enhancing treatment …

ER stress-induced LINC00173 promotes the apoptosis of ovarian granulosa cells by regulating the HRK/PI3K/AKT pathway in polycystic ovary syndrome

Y Zhao, X Wu, F Meng, X Liu, J Yuan, X Zhang… - Scientific Reports, 2024 - nature.com
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and metabolic
abnormality disease that mainly affects women of reproductive age. LINC00173, a novel …

The effects of natural products and bioactive ingredients of traditional Chinese medicine on apoptosis of ovarian granulosa cells

L Zhong, Y Luo, F Zhou, X Yang, Y Tan… - Journal of Applied …, 2023 - Wiley Online Library
Abnormal ovarian function is the main manifestation of female reproductive toxicity.
Granulosa cells (GCs) play an important role in determining the fate of follicles and are the …

Ferrostatin-1 ameliorates Cis-dichlorodiammineplatinum (II)-induced ovarian toxicity by inhibiting ferroptosis

L Zhang, Z Dong, F Jiang, H Huang, H Ding, M Liu - Molecular Medicine, 2024 - Springer
Abstract Cis-dichlorodiammineplatinum (II)(CDDP), while widely utilized in tumor therapy,
results in toxic side effects that patients find intolerable. The specific mechanism by which …