The impact of obesity and adipokines on breast and gynecologic malignancies

S Tewari, R Vargas, O Reizes - … of the New York Academy of …, 2022 - Wiley Online Library
The link between obesity and multiple disease comorbidities is well established. In 2003,
Calle and colleagues presented the relationship between obesity and several cancer types …

Novel treatments for obesity: implications for cancer prevention and treatment

CM Cuttica, IM Briata, A DeCensi - Nutrients, 2023 - mdpi.com
It is now established that obesity is related to a higher incidence of cancer during a lifespan.
The effective treatment of obesity opens up new perspectives in the treatment of a relevant …

Targeting adiponectin in breast cancer

R Nehme, M Diab-Assaf, C Decombat, L Delort… - Biomedicines, 2022 - mdpi.com
Obesity and breast cancer are two major health issues that could be categorized as sincere
threats to human health. In the last few decades, the relationship between obesity and …

Clinical impact of glucagon-like Peptide-1 receptor analogs on the complications of obesity

D Yazıcı, H Yapıcı Eser, S Kıyıcı, S Sancak, H Sezer… - Obesity Facts, 2023 - karger.com
Background: Obesity is a chronic disease associated with increased morbidity and mortality
due to its complications. The aims of obesity treatment are primarily to accomplish weight …

[HTML][HTML] Liraglutide attenuates obese-associated breast cancer cell proliferation via inhibiting PI3K/Akt/mTOR signaling pathway

A Alanteet, H Attia, M Alfayez, A Mahmood… - Saudi Pharmaceutical …, 2024 - Elsevier
This study aims to explore the anti-proliferative, pro-apoptotic, and anti-migration activities of
liraglutide (LGT) in MCF-7 breast cancer (BC) cells in subjects with obesity, particularly its …

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of developing cancer-related lymphedema following axillary lymph node dissection …

S Brown, AB Tadros, G Montagna, T Bell… - Frontiers in …, 2024 - frontiersin.org
Purpose Patients undergoing axillary lymph node dissection (ALND) for breast cancer face a
high risk of lymphedema, further increased by high body mass index (BMI) and insulin …

Anti-Diabetic Therapies and Cancer: From Bench to Bedside

D Kounatidis, NG Vallianou, I Karampela, E Rebelos… - Biomolecules, 2024 - mdpi.com
Diabetes mellitus (DM) is a significant risk factor for various cancers, with the impact of anti-
diabetic therapies on cancer progression differing across malignancies. Among these …

GLP-1 receptor agonist as an effective treatment for breast cancer-related lymphedema: a case report

F Crowley, MD Brown, EJ Gallagher, J Dayan - Frontiers in …, 2024 - frontiersin.org
Introduction: Lymphedema is a major public health issue for many women undergoing
breast cancer treatment. Although weight loss has been reported to be beneficial in the …

[HTML][HTML] Glucagon-like peptide-1 analog liraglutide reduces fat deposition in chicken adipocytes

J Zhang, G Yang, J Liu, Z Lin, J Zhang, J Zhao, G Sun… - Poultry Science, 2024 - Elsevier
Previously, we reported that glucagon-like peptide-1 (GLP-1) and its analog liraglutide could
inhibit fat de novo synthesis in the liver and reduce abdominal fat accumulation in broiler …

Combined treatment with glucagon-like peptide-1 receptor agonist exendin-4 and metformin attenuates breast cancer growth

Y Tanaka, C Iwaya, T Kawanami, Y Hamaguchi… - Diabetology …, 2022 - Springer
Cancer is a major cause of death in patients with diabetes. Incretin therapy has received
much attention because of its tissue-protective effects. We have previously reported an anti …