Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE …

SP Patil, IA Ayappa, SM Caples, RJ Kimoff… - Journal of Clinical …, 2019 - jcsm.aasm.org
Introduction: The purpose of this systematic review is to provide supporting evidence for the
clinical practice guideline for the treatment of obstructive sleep apnea (OSA) in adults using …

Increased prevalence of sleep-disordered breathing in adults

PE Peppard, T Young, JH Barnet… - American journal of …, 2013 - academic.oup.com
Sleep-disordered breathing is a common disorder with a range of harmful sequelae. Obesity
is a strong causal factor for sleep-disordered breathing, and because of the ongoing obesity …

Upper-airway stimulation for obstructive sleep apnea

PJ Strollo Jr, RJ Soose, JT Maurer… - … England Journal of …, 2014 - Mass Medical Soc
Background Obstructive sleep apnea is associated with considerable health risks. Although
continuous positive airway pressure (CPAP) can mitigate these risks, effectiveness can be …

Effect of an interdisciplinary weight loss and lifestyle intervention on obstructive sleep apnea severity: the INTERAPNEA randomized clinical trial

A Carneiro-Barrera, FJ Amaro-Gahete… - JAMA Network …, 2022 - jamanetwork.com
Importance Obesity is the leading cause of obstructive sleep apnea (OSA); however, the
effects of weight loss and lifestyle interventions on OSA and comorbidities remain uncertain …

The combination of atomoxetine and oxybutynin greatly reduces obstructive sleep apnea severity. A randomized, placebo-controlled, double-blind crossover trial

L Taranto-Montemurro, L Messineo… - American journal of …, 2019 - atsjournals.org
Rationale: There is currently no effective pharmacological treatment for obstructive sleep
apnea (OSA). Recent investigations indicate that drugs with noradrenergic and …

Obstructive sleep apnea and orthodontics: an American Association of Orthodontists White Paper

RG Behrents, AV Shelgikar, RS Conley… - American journal of …, 2019 - Elsevier
Highlights•Obstructive sleep apnea can have many serious consequences if left
untreated.•OSA can affect adults and children and can present at any time in …

The bidirectional relationship between exercise and sleep: implications for exercise adherence and sleep improvement

CE Kline - American journal of lifestyle medicine, 2014 - journals.sagepub.com
Exercise has long been associated with better sleep, and evidence is accumulating on the
efficacy of exercise as a nonpharmacologic treatment option for disturbed sleep. Recent …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Physical activity and sleep: An updated umbrella review of the 2018 Physical Activity Guidelines Advisory Committee report

CE Kline, CH Hillman, BB Sheppard, B Tennant… - Sleep medicine …, 2021 - Elsevier
Physical activity (PA) is widely considered to improve sleep, but a comprehensive review of
the research on this topic has not been performed. In this umbrella review, conducted …