An escalation in the incidence of oral cancer and its attributable mortality has been observed
in recent decades in Europe; oral cancer is expected to become a public health problem in …

Cell proliferative activity has been extensively investigated in head and neck tumors.
Ki67/MIB-1 immunostaining, tritiated thymidine or bromodeoxyuridine labeling indices, DNA …

Background. Neck metastasis is a major prognostic factor of head and neck carcinoma, but
its preoperative detection is currently unreliable. Molecular markers of the metastatic …

Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm of the nasopharynx
that accounts for 0.5% of all head and neck tumors. Although histologically benign in …

Up to now results concerning the prognostic value of tumor proliferation markers in
squamous cell head and neck carcinoma have been equivocal. Beside biological reasons …

OBJECTIVES: Juvenile nasopharyngeal angiofibroma (JNA) is a highly vascular and locally
invasive tumor that exclusively affects male adolescents. Sex hormones are first discussed …

Apicidin, a cyclic peptide histone deacetylase (HDAC) inhibitor, has been demonstrated to
exhibit antitumor activity in a number of human cancer types. The present study examined …

Objectives Recently published data suggest a prognostic value of immunohistochemical
proliferation markers for limited laryngeal carcinoma. Previous studies have reported …

This retrospective case control study was conducted to assess the prognostic value of some
patient-, tumor-, treatment-related variables, and to correlate markers of primary tumor with …

To assess cytokeratin-17 (CK17) as an immunohistochemical marker for squamous cell
carcinoma of the larynx, we stained 63 tissue samples from 63 consecutive patients who …