Pivotal role of Helicobacter pylori virulence genes in pathogenicity and vaccine development

A Elbehiry, E Marzouk, A Abalkhail, W Sindi… - Frontiers in …, 2025 - frontiersin.org
One of the most prevalent human infections is Helicobacter pylori (H. pylori), which affects
more than half of the global population. Although H. pylori infections are widespread, only a …

Solid Lipid Nanoparticles Delivering a DNA Vaccine Encoding Helicobacter pylori Urease A Subunit: Immune Analyses before and after a Mouse Model of Infection

JE Francis, I Skakic, D Majumdar, AC Taki… - International Journal of …, 2024 - mdpi.com
In this study, novel solid lipid particles containing the adjuvant lipid monophosphoryl lipid A
(termed 'SLN-A') were synthesised. The SLN-A particles were able to efficiently bind and …

Nanocapsules Comprised of Purified Protein: Construction and Applications in Vaccine Research

I Skakic, AC Taki, JE Francis, C Dekiwadia, TTH Van… - Vaccines, 2024 - mdpi.com
Nanoparticles show great promise as a platform for developing vaccines for the prevention
of infectious disease. We have been investigating a method whereby nanocapsules can be …

[PDF][PDF] INFLAMMATION, IMMUNITY, AND VACCINES

R Gong, M Gerhard - microbiotajournal.com
Helicobacter pylori, the most common gastric infection in the world, causes gastritis, peptic
ulcers, and gastric cancer. Innate and adaptive immune responses are induced after H …