Evolution of exon-intron structure of eukaryotic genes has been a matter of long-standing,
intensive debate. The introns-early concept, later rebranded 'introns first'held that protein …

The origins and importance of spliceosomal introns comprise one of the longest-abiding
mysteries of molecular evolution. Considerable debate remains over several aspects of the …

Sequencing of eukaryotic genomes allows one to address major evolutionary problems,
such as the evolution of gene structure. We compared the intron positions in 684 …

In this work we review the current knowledge on the prehistory, origins, and evolution of
spliceosomal introns. First, we briefly outline the major features of the different types of …

Although evidence for horizontal gene transfer (HGT) in eukaryotes remains largely
anecdotal, literature on HGT in fungi suggests that it may have been more important in the …

When the first parallel (~///) 8-barrel of triosephosphate isomerase (TIM) was determined in
1975 (Banner et al., 1975), not many people were able to imagine the scope and the impact …

The availability of multiple, complete eukaryotic genome sequences allows one to address
many fundamental evolutionary questions on genome scale. One such important, long …

Introns are integral elements of eukaryotic genomes that perform various important functions
and actively partici-pate in gene evolution. We review six distinct roles of spliceosomal …

Fall armyworm (Spodoptera frugiperda [JE Smith]) is a moth native to the Western
Hemisphere where it is a major pest of corn (maize) and multiple other crops. It is now a …

Improvement of enzymes is one of the important objectives of biotechnology. In vitro
evolution of enzymes using DNA shuffling involves the assembly of two or more DNA …