Cellular and molecular mechanisms of tooth root development

J Li, C Parada, Y Chai - Development, 2017 - journals.biologists.com
The tooth root is an integral, functionally important part of our dentition. The formation of a
functional root depends on epithelial-mesenchymal interactions and integration of the root …

Advanced biomaterials and techniques for oral tissue engineering and regeneration—a review

A Matichescu, LC Ardelean, LC Rusu, D Craciun… - Materials, 2020 - mdpi.com
The reconstruction or repair of oral and maxillofacial functionalities and aesthetics is a
priority for patients affected by tooth loss, congenital defects, trauma deformities, or various …

Stem cell‐based tooth and periodontal regeneration

L Hu, Y Liu, S Wang - Oral diseases, 2018 - Wiley Online Library
Currently regeneration of tooth and periodontal damage still remains great challenge. Stem
cell‐based tissue engineering raised novel therapeutic strategies for tooth and periodontal …

Therapeutic potential of dental stem cells

EP Chalisserry, SY Nam, SH Park… - Journal of tissue …, 2017 - journals.sagepub.com
Stem cell biology has become an important field in regenerative medicine and tissue
engineering therapy since the discovery and characterization of mesenchymal stem cells …

Mesenchymal condensation in tooth development and regeneration: a focus on translational aspects of organogenesis

BD Sui, CX Zheng, WM Zhao, K Xuan… - Physiological …, 2023 - journals.physiology.org
The teeth are vertebrate-specific, highly specialized organs performing fundamental
functions of mastication and speech, the maintenance of which is crucial for orofacial …

Dental stem cells in tooth regeneration and repair in the future

C Morsczeck, TE Reichert - Expert opinion on biological therapy, 2018 - Taylor & Francis
Introduction: Human dental stem cells can be obtained from postnatal teeth, extracted
wisdom teeth or exfoliated deciduous teeth. Due to their differentiation potential, these …

[HTML][HTML] Stem cells from human exfoliated deciduous teeth as an alternative cell source in bio-root regeneration

X Yang, Y Ma, W Guo, B Yang, W Tian - Theranostics, 2019 - ncbi.nlm.nih.gov
A stem cell-mediated bioengineered tooth root (bio-root) has proven to be a prospective tool
for the treatment of tooth loss. As shown in our previous studies, dental follicle cells (DFCs) …

The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration

P Hilkens, A Bronckaers, J Ratajczak… - Stem Cells …, 2017 - Wiley Online Library
Adequate vascularization, a restricting factor for the survival of engineered tissues, is often
promoted by the addition of stem cells or the appropriate angiogenic growth factors. In this …

[HTML][HTML] Tooth formation: are the hardest tissues of human body hard to regenerate?

J Baranova, D Büchner, W Götz, M Schulze… - International journal of …, 2020 - mdpi.com
With increasing life expectancy, demands for dental tissue and whole-tooth regeneration are
becoming more significant. Despite great progress in medicine, including regenerative …

Personalized 3D‐printed scaffolds with multiple bioactivities for bioroot regeneration

Y Huang, Z Zhang, F Bi, H Tang, J Chen… - Advanced …, 2023 - Wiley Online Library
Recent advances in 3D printing offer a prospective avenue for producing transplantable
human tissues with complex geometries; however, the appropriate 3D‐printed scaffolds …